Clinical, Trichoscopic, and Folliscopic Identification of the Impact of Metabolic Syndrome on the Response to Intradermal Dutasteride 0.02% Injection in Patients with Female Pattern Hair Loss: A Prospective Cohort Study
October 2021
in “
Journal of Dermatological Treatment
”
TLDR Metabolic syndrome reduces effectiveness of hair loss treatment.
A prospective cohort study investigated the impact of metabolic syndrome (MetS) on the response to intradermal dutasteride 0.02% injection in female pattern hair loss (FPHL) patients. The study involved 51 women, with 26 having MetS and 25 without. The study found that MetS can decrease the effectiveness of intradermal dutasteride 0.02% injection for FPHL, resulting in a lower percentage of terminal hair and a higher percentage of vellus hair. However, further research is needed to confirm these findings. Trichoscopy and folliscopy were used to evaluate treatment response. The study also found that the duration of FPHL was significantly related to changes in hair thickness after treatment in patients with MetS.
View this study on tandfonline.com →
Cited in this study
37 / NoResults
research The New Paradigm for Androgenetic Alopecia and Plant-Based Folk Remedies: 5α-Reductase Inhibition, Reversal of Secondary Microinflammation, and Improving Insulin Resistance
Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.
research Alopecia and the metabolic syndrome
Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.
research Further Clinical Evidence for the Effect of IGF-1 on Hair Growth and Alopecia
IGF-1 may affect hair growth and loss, but more research is needed to confirm effective and safe treatments.
research Apoptosis in follicles of individuals with female pattern hair loss is associated with perifollicular microinflammation
Hair loss in women links to inflammation around hair follicles.
research The association of androgenetic alopecia and insulin resistance is independent of hyperandrogenemia: A case-control study
Hair loss is linked to insulin resistance in women, regardless of hormone levels.
research Both low circulating insulin-like growth factor-1 and high-density lipoprotein cholesterol are associated with hair loss in middle-aged women
Low IGF-1 and high HDL cholesterol levels are linked to more hair loss in middle-aged women.
research Association of metabolic syndrome with female pattern hair loss in women: A case-control study
Metabolic syndrome linked to female hair loss; waist size and high blood pressure important factors.
research The impact of oxidative stress on hair
Oxidative stress damages hair and contributes to aging, and managing it can help maintain hair health.
research Is There Really Relationship between Androgenetic Alopecia and Metabolic Syndrome?
No clear link between hair loss and metabolic syndrome, but some differences in blood pressure and glucose levels.
research Alopecia and its association with coronary heart disease and cardiovascular risk factors: A meta-analysis
People with alopecia are at higher risk for heart disease and have more heart-related risk factors.
research Androgenetic alopecia, metabolic syndrome, and insulin resistance: Is there any association? A case-control study
Hair loss linked to metabolic issues and insulin resistance; early assessment may reduce future health risks.
research The use of low-level light therapy in the treatment of androgenetic alopecia and female pattern hair loss
Low-level light therapy may help hair regrowth, but more research is needed.
research Factors associated with female pattern hair loss and its prevalence in Taiwanese women: A community-based survey
FPHL common in Taiwanese women; risk factors include BMI, high glucose, early puberty, fewer childbirths, oral contraceptives, and UV exposure.
research Is Trichoscopy a reliable tool to diagnose early female pattern hair loss?
Trichoscopy effectively diagnoses early female hair loss, but may need scalp biopsy for confirmation.
research Mesotherapy using dutasteride-containing preparation in treatment of female pattern hair loss: photographic, morphometric and ultrustructural evaluation
Dutasteride-containing mesotherapy effectively treats female hair loss, improving density and thickness with minimal side effects.
research Gender-specific association of androgenetic alopecia with metabolic syndrome in a middle-aged Korean population
Female hair loss linked to metabolic syndrome, not in males.
research Clinical severity does not reliably predict quality of life in women with alopecia areata, telogen effluvium, or androgenic alopecia
How bad a woman's hair loss is doesn't always match how it affects her happiness and daily life.
research Guidelines for the management of androgenetic alopecia (2010)
Use minoxidil for hair loss treatment, and finasteride for men.
research Male pattern baldness and the risk of prostate cancer
Men who experienced baldness at age 20 may have double the risk of getting prostate cancer.
research The investigation of insulin resistance and metabolic syndrome in male patients with early-onset androgenetic alopecia
Early balding men may have insulin resistance, but lifestyle changes can help.
research S1 guideline for diagnostic evaluation in androgenetic alopecia in men, women and adolescents
Guidelines for diagnosing common hair loss include detailed history, clinical examination, and various diagnostic techniques.
research Androgenetic alopecia and cardiovascular risk factors in men and women: A comparative study
Hair loss linked to higher heart disease risk in both men and women.
research Association of androgenetic alopecia with metabolic syndrome in men: a community-based survey
Balding men, especially young ones, may have higher risk of heart issues and diabetes; check cholesterol levels.
research Alopecia androgénica masculina y factores de riesgo cardiovascular: estudio de casos y controles
Men with early-onset baldness have a higher chance of heart disease and clogged arteries.
research Dermoscopy in female androgenic alopecia: Method standardization and diagnostic criteria
Trichoscopy can diagnose female hair loss with high accuracy by looking for specific patterns in hair and scalp appearance.
research Survivin in the Human Hair Follicle
Survivin protein is crucial for hair growth and preventing cell death in hair follicles.
research Prevalence of Male and Female Pattern Hair Loss in Maryborough
Hair loss common in Australia; men affected earlier, more often than Asians; women less concerned.
research Marked Suppression of Dihydrotestosterone in Men with Benign Prostatic Hyperplasia by Dutasteride, a Dual 5α-Reductase Inhibitor
Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.
research Molecular mechanisms of androgenetic alopecia
AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.
research Female pattern hair loss
Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.
research Towards a molecular understanding of hair loss and its treatment
Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.
research Early Onset of Androgenetic Alopecia Associated With Early Severe Coronary Heart Disease: A Population-Based, Case-Control Study
Early balding linked to higher heart disease risk.
research The psychology of hair loss and its implications for patient care
Hair loss can significantly affect a person's self-esteem and body image, especially in young people, those who value their looks highly, and women.
research Androgenetic alopecia and microinflammation
Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.
research Finasteride in the treatment of men with frontal male pattern hair loss
Finasteride effectively treats frontal hair loss with few side effects.
research Psychological characteristics of women with androgenetic alopecia: a controlled study
Women with AGA often face anxiety, depression, and low self-esteem; psychological support is important.
research Classification of the types of androgenetic alopecia (common baldness) occurring in the female sex
Common baldness, also known as Androgenetic Alopecia, is caused by a combination of genetic factors and hormones called androgens.
Related
9 / NoResults
research Clinical, Trichoscopic, and Folliscopic Identification of the Impact of Metabolic Syndrome on the Response to Intradermal Dutasteride 0.02% Injection in Patients with Female Pattern Hair Loss: A Prospective Cohort Study
Metabolic syndrome reduces effectiveness of hair loss treatment.
research Hair Loss in Adult Females: A Clinical and Trichoscopic Study
Most adult women experiencing hair loss are aged 21-40, with the most common type being female pattern hair loss. Trichoscopy is a useful tool for diagnosing different types of hair loss.
research Hair Disorders
The document's conclusion cannot be provided because the document cannot be parsed.
research Frontal fibrosing alopecia
Frontal fibrosing alopecia is a scarring hair loss condition mainly affecting older women, with no known cause and treatments that may help stabilize hair loss.
research Alopecia Areata of the Beard: A Review of the Literature
The document concludes that more research is needed to understand and treat Beard Alopecia Areata due to limited current knowledge and evidence.
research 대학병원 피부과 외래에 내원한 안드로겐 및 원형탈모증 환자에서의 대표적 Trichoscopic Finding에 대한 고찰
The document's conclusion cannot be summarized as it is not provided in a language I can understand.
research P171 : Trichoscopic findings in androgenetic alopecia and alopecia areata
research Disorders of Hair
The document's conclusion cannot be provided because the document is not readable or understandable.
research Trichoscopy for common hair loss diseases: Algorithmic method for diagnosis
The conclusion is that an algorithm using trichoscopy helps diagnose different types of hair loss but may need updates and a biopsy if results are unclear.