Protective Activity against Oxidative Stress in Dermal Papillae with Extracted Herbal Essential Oils

    March 2023 in “Applied sciences
    Da-In Choi, Jee‐Young Jasmine Choi, Jee-Bum Lee, Sook-Jung Yun, Byung-Kwon Moon, Yong-Gook Ahn, Sook-Young Lee, Seung−Chul Lee
    TLDR Lavender, lemongrass, rosemary, and chamomile essential oils may help protect cells important for hair growth from damage and could promote hair growth.
    The study investigated the effects of lavender, lemongrass, rosemary, and chamomile essential oils on dermal papilla cells (DPCs), which are crucial for hair growth. The oils were found to reduce reactive oxygen species (ROS) production, a cause of oxidative stress linked to hair loss. They also increased the expression of NRF-2, a protein that regulates the cellular response to oxidative stress, and phase II enzymes, which have antioxidant effects. Additionally, the oils upregulated the expression of Vascular Endothelial Growth Factor (VEGF) and Insulin-like Growth Factor 1 (IGF-1), biomarkers associated with hair growth. These findings suggest that these essential oils may protect DPCs from oxidative stress and promote hair growth.
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