Preventive Effects of Cedrol Against Alopecia in Cyclophosphamide-Treated Mice

    Shanshan Chen, Yan Zhang, Qiu-Li Lu … Yuqing Zhao
    Studysummary In this animal study, cedrol treatment reduced chemotherapy-induced alopecia in mice by preventing hair follicle damage, while minoxidil did not prevent alopecia under similar conditions.
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    Research cited in this study 14

    1. Treatment and Prevention of Chemotherapy-Induced Alopecia with PTH-CBD, a Collagen-Targeted Parathyroid Hormone Analog, in a Non-Depilated Mouse Model Anti-Cancer Drugs · 2013
    2. Pathobiology of Chemotherapy-Induced Hair Loss The Lancet Oncology · 2013
    3. Hair Shaft Abnormalities After Chemotherapy and Tamoxifen Therapy in Patients With Breast Cancer Evaluated by Optical Coherence Tomography British Journal of Dermatology · 2012
    4. Chemoprevention of Doxorubicin-Induced Alopecia in Mice by Dietary Administration of L-Cystine and Vitamin B6 Archives of Dermatological Research · 2012
    5. P53-Dependent Transcriptional Regulation of EDA2R and Its Involvement in Chemotherapy-Induced Hair Loss FEBS Letters · 2010
    6. Chemoprevention of Smoke-Induced Alopecia in Mice by Oral Administration of L-Cystine and Vitamin B6 Journal of dermatological science · 2007
    7. Chemotherapy Targets the Hair Follicle Vascular Network but Not the Stem Cells Journal of Investigative Dermatology · 2006
    8. In Vitro Differences Between Keratinocyte Stem Cells and Transit-Amplifying Cells of the Human Hair Follicle Journal of Investigative Dermatology · 2005
    9. Hair Follicle-Derived Blood Vessels Vascularize Tumors in Skin and Are Inhibited by Doxorubicin Cancer Research · 2005
    10. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    11. Defolliculated (Dfl): A Dominant Mouse Mutation Leading to Poor Sebaceous Gland Differentiation and Total Elimination of Pelage Follicles Journal of Investigative Dermatology · 2002
    12. Topical Application of Cyclosporin A Induces Rapid Remodeling of Damaged Anagen Hair Follicles in Cyclophosphamide-Administered Mice Journal of Dermatological Science · 2001
    13. A Randomized Trial of Minoxidil in Chemotherapy-Induced Alopecia Journal of The American Academy of Dermatology · 1996
    14. Growth of the Hair Physiological Reviews · 1954

    Related research 7

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    2. Hair-Growth Potential of Ginseng and Its Major Metabolites: A Review on Its Molecular Mechanisms International Journal of Molecular Sciences · 2018
    3. Preventive Effects of Cedrol Against Alopecia in Cyclophosphamide-Treated Mice Environmental Toxicology and Pharmacology · 2016
    4. Androgenetic Alopecia and Its Remedies: A Review Journal of drug discovery and therapeutics · 2014
    5. Alopecia Journal of the Korean Medical Association · 2002
    6. Treatment of Hair Loss The New England Journal of Medicine · 1999
    7. Chapter 20: Pathogenesis and Treatment of Alopecias Annual Reports in Medicinal Chemistry · 1989