Hair Growth Promotion by Extracts of Inula Helenium and Caesalpinia Sappan Bark in Patients with Androgenetic Alopecia: A Pre-Clinical Study Using Phototrichogram Analysis

    November 2019 in “ Cosmetics ”
    Hyoung Jin Choi, Gae Won Nam, Noh-Hee Jeong, Bu Young Choi
    Studysummary In this clinical study, researchers observed that a shampoo formulated with Inula helenium and Caesalpinia Sappan extracts significantly increased total hair count after 16 and 24 weeks in patients with androgenetic alopecia, suggesting it may help prevent hair loss and promote hair growth.
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    Research cited in this study 12

    1. Costunolide: A Bioactive Sesquiterpene Lactone with Diverse Therapeutic Potential International Journal of Molecular Sciences · 2019
    2. Costunolide Promotes the Proliferation of Human Hair Follicle Dermal Papilla Cells and Induces Hair Growth in C57BL/6 Mice Journal of Cosmetic Dermatology · 2018
    3. 3-Deoxysappanchalcone Promotes Proliferation of Human Hair Follicle Dermal Papilla Cells and Hair Growth in C57BL/6 Mice by Modulating WNT/β-Catenin and STAT Signaling Biomolecules & Therapeutics · 2016
    4. Efficacy of Cistanche Tubulosa and Laminaria Japonica Extracts (MK-R7) Supplement in Preventing Patterned Hair Loss and Promoting Scalp Health Clinical Nutrition Research · 2015
    5. Effects of a New Mild Shampoo for Preventing Hair Loss in Asians Using a Simple Hand-Held Phototrichogram Technique International Journal of Cosmetic Science · 2011
    6. Raising Hairs Nature Biotechnology · 2011
    7. Finasteride: Its Impact on Sexual Function and Prostate Cancer Journal of Cutaneous and Aesthetic Surgery · 2009
    8. A New Classification of Pattern Hair Loss That Is Universal for Men and Women: Basic and Specific (BASP) Classification Journal of The American Academy of Dermatology · 2007
    9. Bioengineering the Hair Follicle Organogenesis · 2007
    10. Human Hair Growth Enhancement In Vitro By Green Tea Epigallocatechin-3-Gallate (EGCG) Phytomedicine · 2006
    11. Identification of Androgen-Inducible TGF-β1 Derived from Dermal Papilla Cells as a Key Mediator in Androgenetic Alopecia Journal of Investigative Dermatology Symposium Proceedings · 2003
    12. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002

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