Effect of Flutamide and Two Novel Synthetic Steroids on GABA, Glutamine, and Some Oxidative Stress Markers in Rat Brain and Prostate

    January 2011 in “ Andrologia ”
    David Calderón Guzmán, Eugene Bratoeff, Erick Gómez Tagle López … Daniel Santamaría del Ángel
    Studysummary This study concluded that 16β-methyl-17α-benzoyloxypregnen-4-en-3,20-dione may be a promising treatment for androgen-dependent diseases and epilepsy due to its antioxidant effects and impact on GABAergic and serotonergic metabolism in rats.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on onlinelibrary.wiley.com →
    Discuss this study in the Community →

    Research cited in this study 3

    1. Attenuating 5α-Pregnane-3α-Ol-20-One Formation in the Hippocampus of Female Rats Increases Pentylenetetrazole-Induced Seizures Epilepsy & Behavior · 2005
    2. Steroid 5α-Reductase Inhibitors Mini-reviews in Medicinal Chemistry · 2003
    3. Effect of a Novel Steroid (PM-9) on the Inhibition of 5α-Reductase in Penicillium Crustosum Broths Steroids · 2003