Effectiveness of Combined Oral Minoxidil and Finasteride in Male Androgenetic Alopecia: A Retrospective Service Evaluation

    January 2025 in “ Cureus
    Hans Johnson, David T. Huang, Ashley K. Clift, Ângela Cristine Bersch-Ferreira, Gustavo Cardoso Guimarães
    Image of study
    TLDR Combined oral minoxidil and finasteride significantly improve hair density in men with male pattern baldness.
    The study involving 502 men with male androgenetic alopecia found that a combined oral minoxidil-finasteride regimen significantly improved hair density over 12 months, with 92.4% of participants experiencing stable or improved hair density and 57.4% showing marked improvements. Even severe cases showed substantial gains, suggesting the treatment's effectiveness beyond mild cases. Despite positive outcomes, the study's retrospective design and modest inter-rater reliability highlight the need for more rigorous trials to confirm findings and optimize treatment protocols. Future research should focus on incorporating patient-reported outcomes and AI-driven methods for better assessment accuracy.
    Discuss this study in the Community →

    Research cited in this study

    23 / 23 results

    Related Community Posts Join

    6 / 1000+ results
      [object Object]

      community 1 month Pyrilutamide. A non responders story to everything.

      in Research/Science  218 upvotes 2 years ago
      My hairline, I am only 23. This conversation is about a user's experience with treatments for androgenic alopecia, including finasteride, dutasteride, RU, minoxidil, progesterone, melatonin, LLLT, oral minoxidil, and Pyrilutamide. They have tried many treatments over the course of two years without seeing much success, and they are considering getting a hair system as a last resort.

      community What else is good. Besides the big 3.

      in Chat  34 upvotes 3 months ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community 3 months progress on fin and min + micro needling (19m)

      in Progress Pictures  762 upvotes 1 year ago
      A 19-year-old male shared his 3-month hair regrowth progress using finasteride, minoxidil, and microneedling, with noticeable improvement. He uses 1mg oral finasteride daily, 5% minoxidil foam twice a day after day 80, and microneedles with a 1.5mm derma stamp every 1-2 weeks.

      community Stopped minoxidil for a year after a year of using it. Starting again.

      in Minoxidil  158 upvotes 2 years ago
      ? This post by PastelDeUva discusses their experience with Minoxidil and Finasteride for hair loss treatments, which they stopped using for a year before resuming due to family's negative opinion. After restarting, they posted photos of the progression/regression of their hairline and are now planning on adding finasteride and dermarolling in order to get good results.

    Related Research

    8 / 8 results