Case Report: Omalizumab-Associated Hair Loss: A Case of Eyebrow Alopecia Areata, Literature Review and FAERS Database Analysis

    June 2025 in “ Frontiers in Medicine ”
    Qian Wang, Lei Hua, Ge Yang … Xiyuan Zhou
    Studysummary This study observed that omalizumab may induce alopecia, particularly in females aged 18-60, though establishing a direct cause-effect link remains challenging. Alopecia areata was noted as a possible uncommon, yet transient, hair loss type associated with omalizumab.
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    Research cited in this study 11

    1. Dupilumab and Alopecia Areata: A Possible Combined or Disturbance Therapy? A Review of the Literature Dermatology Practical & Conceptual · 2024
    2. Drug-Induced Hair Loss: Analysis of the Food and Drug Administration’s Adverse Events Reporting System Database Skin Appendage Disorders · 2024
    3. Alopecia Due to Chemotherapeutics, Hedgehog Inhibitors, Targeted Antibody Therapies, and Immune Checkpoint Inhibitors Deleted Journal · 2024
    4. Deciphering the Complex Immunopathogenesis of Alopecia Areata International Journal of Molecular Sciences · 2024
    5. A Cross-Sectional Analysis of Medications Used by Patients Reporting Alopecia Areata on the FDA Adverse Events Reporting System International Journal of Dermatology · 2024
    6. Drug-Induced Alopecia Areata: A Systematic Review Journal of the American Academy of Dermatology · 2023
    7. Comparative Evaluation of the Efficacy of Topical Tacrolimus 0.03% and Topical Calcipotriol 0.005% Mixed With Betamethasone Dipropionate Versus Topical Clobetasol 0.05% in Treatment of Alopecia Areata: A Clinical and Trichoscopic Study Journal of cosmetic dermatology · 2022
    8. Telogen Effluvium: A Review of the Literature Cureus · 2020
    9. Alopecia Areata After Omalizumab Treatment for Chronic Spontaneous Urticaria Acta Dermato Venereologica · 2019
    10. Alopecia Areata After Dupilumab for Atopic Dermatitis JAAD case reports · 2018
    11. Transient Hair Loss in Patients With Chronic Spontaneous Urticaria Treated With Omalizumab European Annals of Allergy and Clinical Immunology · 2017

    Related research 4

    1. Alopecia Areata: A Multifactorial Autoimmune Condition Journal of autoimmunity · 2018
    2. Linear Alopecia Areata JAAD case reports · 2018
    3. Treating Resistant Cases of Alopecia Universalis Journal of cosmetology & trichology · 2018
    4. Overview of Alopecia Areata ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2013