Efficacy of Platelet Rich Plasma and Concentrated Growth Factor in Treating Androgenetic Alopecia: A Split-Scalp Study

September 2025 in “ Journal of Maxillofacial and Oral Surgery ”

Madan Mishra, Rasesh D. Varia, Shubhamoy Mondal, Gaurav Singh, Amit Gaur, Abhinav Srivastava

platelet-rich plasma concentrated growth factor androgenetic alopecia hair regrowth hair count hair density hair pull test PRP CGF AGA

TLDR Combining PRP with CGF is more effective for hair regrowth in androgenetic alopecia than PRP alone.

This study investigated the effectiveness of platelet-rich plasma (PRP) alone versus PRP combined with concentrated growth factor (CGF) in treating androgenetic alopecia (AGA) in a split-scalp trial involving 20 patients. The results showed that both treatments led to significant hair regrowth, but the combination of PRP and CGF (Site II) was more effective, with greater increases in hair count and density, higher patient satisfaction, and better hair pull test outcomes compared to PRP alone (Site I). The study suggests that PRP combined with CGF offers a superior non-surgical treatment option for AGA, though further long-term studies are recommended for optimizing the treatment protocol.

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Research cited in this study

12 / 12 results

Evaluation of the Safety and Efficacy of Concentrated Growth Factors for Hair Growth Promotion in Androgenetic Alopecia Patients: A Retrospective Single-Center, Single-Arm Study

research Evaluation of the Safety and Efficacy of Concentrated Growth Factors for Hair Growth Promotion in Androgenetic Alopecia Patients: A Retrospective Single-Center, Single-Arm Study

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research Platelet-Rich Plasma as a Therapy for Androgenic Alopecia: A Systematic Review and Meta-Analysis

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Stem Cells from Human Hair Follicles: First Mechanical Isolation for Immediate Autologous Clinical Use in Androgenetic Alopecia and Hair Loss

research Stem Cells from Human Hair Follicles: First Mechanical Isolation for Immediate Autologous Clinical Use in Androgenetic Alopecia and Hair Loss

86 citations , June 2017 in “Stem cell investigation”

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Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

research Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

136 citations , April 2016 in “Dermatologic Surgery”

PRP treatment helps hair growth and density in androgenetic alopecia patients.

research Platelet-Rich Plasma for Androgenetic Alopecia

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research Study of Platelet-Rich Plasma Injections in the Treatment of Androgenetic Alopecia Through a One-Year Period

164 citations , January 2014 in “Journal of Cutaneous and Aesthetic Surgery”

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research The Effect of Autologous Activated Platelet Rich Plasma Injection on Pattern Hair Loss: Clinical and Histomorphometric Evaluation

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AA-PRP injections effectively increase hair count and thickness for male pattern hair loss.

research Platelet-Rich Plasma in Androgenic Alopecia: Myth or Effective Tool

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Platelet-rich plasma (PRP) is a cheap and easy treatment for hair loss, but not suitable for everyone. It also helps in healing ulcers, rejuvenating skin, and improving hair transplants.

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Platelet-rich plasma with a new carrier significantly increases hair thickness without serious side effects.

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