Design, Synthesis, and Biological Activity of TLR7-Based Compounds for Chemotherapy-Induced Alopecia

    July 2019 in “ Investigational new drugs ”
    Jincheng Yang, Kun Chen, Bin Wang … Weihua Wang
    Studysummary TLR7-based compounds may help manage chemotherapy-induced hair loss.
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    Research cited in this study 12

    1. Cancer Risk in Patients with Alopecia Areata: A Nationwide Population-Based Matched Cohort Study Cancer Medicine · 2018
    2. Pathogenesis and Treatment Options for Chemotherapy-Induced Alopecia: A Systematic Review International Journal of Dermatology · 2018
    3. Protective Mechanism of Adipose-Derived Stem Cells in Remodeling of the Skin Stem Cell Niche During Photoaging Cellular Physiology and Biochemistry · 2018
    4. Effects of Imiquimod on Hair Follicle Stem Cells and Hair Cycle Progression ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2016
    5. The Use of Scalp Cooling for Chemotherapy-Induced Hair Loss British journal of nursing · 2016
    6. Alopecia in General Medicine Clinical Medicine · 2016
    7. Isolation of Mouse Hair Follicle Bulge Stem Cells and Their Functional Analysis in a Reconstitution Assay Methods in molecular biology · 2016
    8. Treatment and Prevention of Chemotherapy-Induced Alopecia with PTH-CBD, a Collagen-Targeted Parathyroid Hormone Analog, in a Non-Depilated Mouse Model Anti-Cancer Drugs · 2013
    9. Pathobiology of Chemotherapy-Induced Hair Loss The Lancet Oncology · 2013
    10. Chemotherapy-Induced Alopecia: Emotional Distress and Mitigation Strategies Seminars in Cutaneous Medicine and Surgery · 2009
    11. Protection Against Chemotherapy-Induced Alopecia Pharmaceutical Research · 2006
    12. The Biology of Hair Follicles The New England Journal of Medicine · 1999