research Design, synthesis, and biological activity of TLR7-based compounds for chemotherapy-induced alopecia
TLR7-based compounds may help manage chemotherapy-induced hair loss.
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5 / 178 resultsresearch SARS-CoV-2 Spike Protein S1-Mediated Endothelial Injury and Pro-Inflammatory State Is Amplified by Dihydrotestosterone and Prevented by Mineralocorticoid Antagonism
This study observed that in vitro exposure to dihydrotestosterone worsened COVID-19 spike protein-induced endothelial injury, while spironolactone showed potential in reducing this effect, suggesting a rationale for further evaluation in treating COVID-19.
research Skin toxicity caused by EGFR antagonists—An autoinflammatory condition triggered by deregulated IL‐1 signaling?
This article explores potential mechanisms of acneiform skin eruptions linked to EGFR inhibition in cancer patients, focusing on EGFR's role in controlling IL-1-dependent inflammation at hair follicles, but reports no clinical results.
research The immune response to COVID‐19: Does sex matter?
This review discusses sex differences in immune responses to COVID-19 and highlights that males tend to experience more severe symptoms and higher mortality but reports no new clinical findings.
research Inflammation in androgenetic alopecia and hair loss: linking neurosciences-endocrinology-dermatology
This article reviews the genetic and androgenic factors influencing the development of androgenetic alopecia and reports no new findings; the authors highlight a need for further research into the underlying mechanisms.
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