Minoxidil Sulfotransferase, A Marker Of Human Keratinocyte Differentiation

    May 1992 in “ Journal of Investigative Dermatology ”
    Garland A. Johnson, Carolyn D. Baker, Karen Knight
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    TLDR Minoxidil sulfotransferase is a marker of keratinocyte differentiation and may play a role in hair growth.
    This study from 31 years ago investigated the nature of minoxidil sulfotransferase activity in epithelial tissue and found that it is a marker of keratinocyte differentiation and distinct from cholesterol sulfotransferase. The study suggests that minoxidil sulfotransferase may play a role in hair growth. The researchers also found that the differentiation process is marked by the induction of a second sulfotransferase that results in the sulfation of minoxidil, but the relevance of this sulfotransferase remains to be determined.
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      community Being Safe on Oral Minoxidil: tl;dr on the literature.

      in Research/Science  47 upvotes 1 week ago
      Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

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