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research Role of cholesterol sulfate in epidermal structure and function: Lessons from X-linked ichthyosis

87 citations , March 2014 in “Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids”

This paper discusses X-linked ichthyosis and its genetic causes, focusing on biochemical pathways and their role in epidermal differentiation and barrier function, but it presents no new clinical findings.

research Sulphation catalysed by the human cytosolic sulphotransferases - chemical defence or molecular terrorism?

48 citations , July 1996 in “Human & Experimental Toxicology”

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

research Skin steroidogenesis in health and disease

47 citations , September 2016 in “Reviews in endocrine and metabolic disorders”

This review discusses the steroidogenic properties of human skin and suggests that impaired steroidogenesis may be linked to conditions like acne, rosacea, atopic dermatitis, and androgenic alopecia, but reports no new clinical results.

research The hair growth effect of minoxidil

1 citations , January 1992 in “Juntendō Igaku/Juntendo igaku”

This review discusses the hair growth mechanisms of minoxidil, suggesting both increased blood flow and a direct effect on hair follicles, but reports no new clinical results.

research Positive Impact of Fish Oil on Diabetic and Hypercholestrolemic Skin Disorders

1 citations , January 2015 in “Journal of nutrition & health”

This study suggests that fish oil, specifically its components EPA and DHA, play a beneficial role in promoting skin health by supporting epidermal growth and reducing proinflammatory cytokines.

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community Could the salicylic acid in my Nioxin shampoo reduce minoxidil effectiveness?

in Minoxidil 3 upvotes 7 months ago

Salicylic acid in Nioxin shampoo may reduce minoxidil effectiveness by inhibiting sulfotransferase activity, potentially causing hair loss. Users suggest stopping salicylic acid use or trying alternative treatments like high-concentration tretinoin or medicated minoxidil/finasteride shampoos.

community Minoxidil Response Bottlenecks: Why Sulfation and Transport Matter (And Where Tretinoin Fits In)

in Research 461 upvotes 1 year ago

Minoxidil's effectiveness is limited by the need for sulfation and proper transport to hair follicles, with tretinoin potentially enhancing its effects by promoting enzyme activity and keratinocyte differentiation. Tretinoin may improve minoxidil's response by boosting the expression of necessary enzymes and transporters.

community 1.25mg oral minoxidil-3 month progress

in Progress Pictures 633 upvotes 1 year ago

A 44-year-old man experienced significant hair regrowth after switching from topical to 1.25mg oral minoxidil and 0.5mg daily finasteride, with no side effects. He noticed hair thickening after two months and credits the oral form's effectiveness.

community High cholesterol causes hair loss?

16 upvotes 2 years ago

High cholesterol may lead to hair loss by causing cicatricial alopecia, an inflammatory disorder. Treatments discussed include cholesterol medication and statins.

community Dutasteride and elevated (LDL) cholesterol

1 upvotes 1 year ago

The user switched from finasteride to dutasteride for hair loss and noticed elevated cholesterol levels, questioning if dutasteride caused this change. They also take Vitamin D, biotin, magnesium, ginkgo biloba, omega-3, and NAC, and are concerned about the impact of these supplements and their health on cholesterol levels.

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