Clinical Efficacy of Adipocyte-Derived Stem Cells Conditioned Media Combined with Micro-Injury in Refractory Patch of Alopecia Areata

    June 2021 in “ Archives of Dermatological Research ”
    Seon Bok Lee, Hyun‐Tae Shin, Ji Won Byun … Gwang Seong Choi
    Studysummary In this study, researchers evaluated the use of adipocyte-derived stem cell conditioned media combined with fractional laser or microneedling for treating refractory alopecia areata, finding that 64.3% of patients had significant hair regrowth, suggesting this combination may be an effective and safe treatment option.
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    Research cited in this study 15

    1. Systematic Review of the Therapeutic Roles of Adipose Tissue in Dermatology Journal of The American Academy of Dermatology · 2018
    2. Alopecia Areata: Overview and Insights from January 2018 Journal of The American Academy of Dermatology · 2017
    3. Microneedling for the Treatment of Hair Loss Journal of The European Academy of Dermatology and Venereology · 2017
    4. Review of Applications of Microneedling in Dermatology Clinical, Cosmetic and Investigational Dermatology · 2017
    5. Stem Cell Therapy as a Novel Therapeutic Intervention for Resistant Cases of Alopecia Areata and Androgenetic Alopecia Journal of Dermatological Treatment · 2016
    6. Hair Regrowth in Alopecia Areata Patients Following Stem Cell Educator Therapy BMC medicine · 2015
    7. Erbium: YAG Laser (2,940 nm) Treatment Stimulates Hair Growth Through Upregulating Wnt 10b and β-Catenin Expression in C57BL/6 Mice PubMed · 2015
    8. Transepidermal Drug Delivery: A New Treatment Option for Areata Alopecia? Journal of cosmetic and laser therapy · 2014
    9. Alopecia Areata: Successful Outcome with Microneedling and Triamcinolone Acetonide Journal of Cutaneous and Aesthetic Surgery · 2014
    10. A Randomized, Double-Blind, Placebo- and Active-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata British Journal of Dermatology · 2013
    11. Histopathology of Alopecia Areata, Acute and Chronic: Why Is It Important to the Clinician? Dermatologic Therapy · 2011
    12. Alopecia Areata Update Journal of the American Academy of Dermatology · 2010
    13. Hair Growth Stimulated by Conditioned Medium of Adipose-Derived Stem Cells Is Enhanced by Hypoxia: Evidence of Increased Growth Factor Secretion Biomedical research · 2010
    14. Hair Growth Promoting Effects of Adipose Tissue-Derived Stem Cells Journal of Dermatological Science · 2009
    15. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007

    Related research 1

    1. Serum Zinc Concentration in Patients With Alopecia Areata Acta dermato-venereologica (Print) · 2023