Comparison of Safety and Efficacy of Topical Mometasone 0.1% Ointment, Calcipotriol 0.005% Ointment, and Tacrolimus 0.1% Ointment in Patients with Localized Alopecia Areata: A Triple-Arm Randomized Clinical Study

    February 2025 in “ Indian Dermatology Online Journal ”
    Farheen Begum, Sasmita Mishra, Ajaya Kumar Jena, Maitreyee Panda
    Studysummary The study found that both mometasone and calcipotriol ointments effectively reduced alopecia severity in localized alopecia areata, with calcipotriol having fewer side effects, while tacrolimus showed no significant effect.
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    Research cited in this study 12

    1. The Efficacy and Safety of JAK Inhibitors for Alopecia Areata: A Systematic Review and Meta-Analysis of Prospective Studies Frontiers in pharmacology · 2022
    2. Efficacy and Safety of Topical Calcipotriol 0.005% Versus Topical Clobetasol 0.05% in the Management of Alopecia Areata: An Intrasubject Pilot Study Dermatology and therapy · 2020
    3. Comparative Study of Efficacy of Topical Mometasone with Calcipotriol Versus Mometasone Alone in the Treatment of Alopecia Areata International Journal of Trichology · 2019
    4. Treatment of Alopecia Areata: An Australian Expert Consensus Statement Australasian journal of dermatology · 2018
    5. Use of Adapalene in Alopecia Areata: Efficacy and Safety of Mometasone Furoate 0.1% Cream Versus Combination of Mometasone Furoate 0.1% Cream and Adapalene 0.1% Gel in Alopecia Areata Dermatologic Therapy · 2017
    6. Efficacy and Safety of Topical Calcipotriol in Management of Alopecia Areata: A Pilot Study Dermatologic Therapy · 2017
    7. Topical Calcipotriol Therapy for Mild-to-Moderate Alopecia Areata: A Retrospective Study PubMed · 2015
    8. Bimatoprost Versus Mometasone Furoate in the Treatment of Scalp Alopecia Areata: A Pilot Study Dermatology · 2015
    9. Randomized Comparison of Topical Betamethasone Valerate Foam, Intralesional Triamcinolone Acetonide, and Tacrolimus Ointment in Management of Localized Alopecia Areata International journal of trichology · 2011
    10. Bexarotene Gel: A New Topical Therapy for Alopecia Areata International journal of trichology · 2010
    11. The Role of Scalp Dermoscopy in the Diagnosis of Alopecia Areata Incognita Journal of The American Academy of Dermatology · 2008
    12. Alopecia in the United States: Outpatient Utilization and Common Prescribing Patterns Journal of the American Academy of Dermatology · 2007

    Related research 1

    1. Twenty Nail Dystrophy with Alopecia Areata in an Atopic Child International journal of research in dermatology · 2019