The Role of Adipocytes in Tissue Regeneration and Stem Cell Niches

    Brett A. Shook, Guillermo C. Rivera-Gonzalez, Sarah Ebmeier … Valerie Horsley
    Studysummary This review explores the novel roles of white adipose tissue in tissue homeostasis and regeneration, emphasizing its impact on epithelial, muscle, and immune tissues, and reports no new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 19

    1. Macrophages Contribute to the Cyclic Activation of Adult Hair Follicle Stem Cells PLoS Biology · 2014
    2. Leptin of Dermal Adipose Tissue Is Differentially Expressed During the Hair Cycle and Contributes to Adipocyte-Mediated Growth Inhibition of Anagen-Phase Vibrissa Hair Experimental Dermatology · 2014
    3. Syndecan-1 Is Required to Maintain Intradermal Fat and Prevent Cold Stress PLOS genetics · 2014
    4. Defining Dermal Adipose Tissue Experimental Dermatology · 2014
    5. Epidermal Wnt/β-Catenin Signaling Regulates Adipocyte Differentiation via Secretion of Adipogenic Factors Proceedings of the National Academy of Sciences of the United States of America · 2014
    6. Leptin Controls Hair Follicle Cycling Experimental Dermatology · 2014
    7. Distinct Fibroblast Lineages Determine Dermal Architecture in Skin Development and Repair Nature · 2013
    8. Hair Cycle Control by Leptin as a New Anagen Inducer Experimental Dermatology · 2013
    9. Intradermal Adipocytes Mediate Fibroblast Recruitment During Skin Wound Healing Development · 2013
    10. Competitive Balance of Intrabulge BMP/Wnt Signaling Reveals a Robust Gene Network Ruling Stem Cell Homeostasis and Cyclic Activation Proceedings of the National Academy of Sciences · 2013
    11. Mesenchymal–Epithelial Interactions During Hair Follicle Morphogenesis and Cycling Seminars in Cell & Developmental Biology · 2012
    12. Identification of Stem Cell Populations in Sweat Glands and Ducts Reveals Roles in Homeostasis and Wound Repair Cell · 2012
    13. Live Imaging of Stem Cell and Progeny Behavior in Physiological Hair-Follicle Regeneration Nature · 2012
    14. Obesity and the Skin British Journal of Dermatology · 2011
    15. Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling Cell · 2011
    16. Skin Signs in Anorexia Nervosa Dermato-endocrinology · 2009
    17. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    18. Obesity and the Skin: Skin Physiology and Skin Manifestations of Obesity Journal of The American Academy of Dermatology · 2007
    19. Defining BMP Functions in the Hair Follicle by Conditional Ablation of BMP Receptor IA The Journal of Cell Biology · 2003