Injections of platelet‐rich plasma prepared by automatic blood cell separator combined with topical 5% minoxidil in the treatment of male androgenetic alopecia
June 2023
in “Skin Research and Technology”
TLDR
Using platelet-rich plasma injections and 5% minoxidil topically can safely and effectively treat mild-to-moderate male pattern baldness.
The study involved 30 male patients with mild-to-moderate androgenetic alopecia (AGA), divided into two groups. Group A received platelet-rich plasma (PRP) injections and topical 5% minoxidil, while Group B received PRP injections and a topical placebo. After 3 months of treatment, 93.3% of patients in Group A showed clinical improvement, compared to 73.3% in Group B. Hair density increased significantly in all patients, but there was no significant difference between the two groups. Patient satisfaction was higher in Group A (86%) than in Group B (73%). The study concluded that PRP injections, prepared by an automatic blood cell separator, combined with topical 5% minoxidil, are safe and effective for treating mild-to-moderate AGA. However, further research with larger sample sizes and longer follow-ups is needed.
View this study on onlinelibrary.wiley.com →
Cited in this study
research Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial considerations, and ethics
research Comparison of 5% minoxidil lotion monotherapy versus its combination with autologous platelet rich plasma in androgenetic alopecia in hundred males
Combination therapy promotes better hair growth and density.
research Treatment of Male-Pattern Alopecia with Platelet-Rich Plasma
Using Platelet-Rich Plasma injections for male-pattern baldness didn't significantly improve hair growth.
research Efficacy of Platelet-rich Plasma for Treating Androgenic Alopecia of Varying Grades
Platelet-rich plasma injections significantly improve hair density and thickness in both male and female pattern hair loss, especially in early stages.
research Genetic and molecular aspects of androgenetic alopecia
research Androgenetic alopecia: a review
Male pattern baldness involves genetics, hormones, and needs better treatments.
research The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial
Platelet-rich plasma injections significantly improved hair regrowth and thickness in patients with hair loss.
research Platelet-rich plasma as a potential treatment for noncicatricial alopecias
Platelet-rich plasma, which carries growth factors, could be a promising treatment for non-scarring hair loss, promoting hair growth and density with no major side effects.
research Guidelines for management of androgenetic alopecia based on BASP classification-the Asian consensus committee guideline
Use 5% minoxidil or oral finasteride for mild-to-moderate hair loss, combine with hair transplant for severe cases.
research Effect of minoxidil on proliferation and apoptosis in dermal papilla cells of human hair follicle
Minoxidil boosts hair growth by increasing cell production and survival.
research The psychosocial consequences of androgenetic alopecia: a review of the research literature
Hair loss affects self-esteem and quality of life; treatments can help.
Related
research Effectiveness of Platelet-Rich Plasma in the Treatment of Androgenic Alopecia Compared to Placebo and Topical Minoxidil: A Systematic Review
research Minoxidil-induced hypertrichosis in a child with alopecia areata
A child used a hair growth lotion for hair loss, but it caused excessive hair growth on his face and neck instead.
research Topical Minoxidil
Minoxidil promotes hair regrowth, but more research needed for effectiveness and response factors.
research Alopecia areata treated with topical minoxidil
Topical minoxidil can help hair regrowth in alopecia areata patients, but maintaining the growth after stopping treatment is inconsistent.