hormone commonly taken for sleep aid has some topical benefits for hair
- Is melatonin better as a supplement or applied to the scalp? No study has compared oral and topical melatonin head to head. Topical melatonin has one small placebo-controlled pilot trial in 40 women plus a set of mostly uncontrolled studies of a cosmetic solution; oral melatonin has no published hair-loss trial at all.
- Adenosine: Is it true it works better for women than men? Why is that? No trial has ever compared topical adenosine in men against women directly, so the claim is unproven. Separate small Japanese trials — 30 women vs placebo over 12 months, 102 men vs niacinamide over 6 months — both reported more thick hairs, so the published evidence is positive in both sexes rather than clearly better in one.
- Alfatradiol: What does a form of estrogen have to do with hair loss in men? Alfatradiol (17α-estradiol) is a prescription topical hormone, licensed for androgenetic alopecia in Germany but not FDA-approved. The controlled trial evidence is in women, where it produced stabilisation rather than regrowth and was outperformed by minoxidil; no comparable placebo-controlled trial in men appears to have been published.
- Does caffeine stimulate hair growth or only slow hair loss? Caffeine stimulates hair follicles in laboratory cultures, and one open-label trial in 210 men found a 0.2% caffeine topical non-inferior to minoxidil 5% on an anagen-ratio endpoint; there is no placebo-controlled evidence that it regrows hair, and none at all in alopecia areata or telogen effluvium.
bioflavonoid found in plants with antioxidant and hair stimulating properties
glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin
natural substance from Neem tree with medicinal and pesticidal properties
