Hypothalamic-Pituitary-Adrenal Axis, Hair, And Sebum: Stress-Mediated Dermatologic Disasters Of The Pandemic Era

    September 2025 in “ Cosmoderma ”
    Krupa Sara Thomas, Abhishek Shanmukha Sai Ponnuri, Shyma K. Latheef … Neha Mohammed Sabu
    Studysummary This study highlights how the COVID-19 pandemic has exacerbated stress-related dermatological issues like acne and hair loss by affecting skin and hair cycles through stress hormones, emphasizing the need for comprehensive psychoneuroendocrine-informed approaches to diagnosis and treatment.
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    Research cited in this study 23

    1. Understanding the Association Between Mental Health and Hair Loss Cureus · 2025
    2. The Hormonal Background of Hair Loss in Non-Scarring Alopecias Biomedicines · 2024
    3. Nanotechnology-Based Techniques for Hair Follicle Regeneration Biomaterials · 2023
    4. Wound-Induced Hair Follicle Neogenesis as a Promising Approach for Hair Regeneration Molecules and Cells · 2023
    5. Psychological Stress-Induced Pathogenesis of Alopecia Areata: Autoimmune and Apoptotic Pathways International journal of molecular sciences · 2023
    6. Systematic Review of Psychological Interventions for Quality of Life, Mental Health, and Hair Growth in Alopecia Areata and Scarring Alopecia Journal of Clinical Medicine · 2023
    7. Integrative and Mechanistic Approach to the Hair Growth Cycle and Hair Loss Journal of Clinical Medicine · 2023
    8. Hair Loss and Telogen Effluvium Related to COVID-19: The Potential Implication of Adipose-Derived Mesenchymal Stem Cells and Platelet-Rich Plasma as Regenerative Strategies International Journal of Molecular Sciences · 2022
    9. Covid Induced Telogen Effluvium: An Insight Indian Dermatology Online Journal · 2022
    10. Association Between Hair Diseases and COVID-19 Pandemic-Related Stress: A Cross-Sectional Study Analysis Frontiers in Medicine · 2022
    11. The Role of SARS-CoV-2 Infection and Its Vaccines in Various Types of Hair Loss Dermatologic Therapy · 2022
    12. Alopecia in Patients with COVID-19: A Systematic Review and Meta-Analysis JAAD International · 2022
    13. Telogen Effluvium Caused by COVID-19 in Elmhurst, New York: Report of a Cohort and Review Dermatology Online Journal · 2021
    14. COVID-19 Induced Telogen Effluvium Dermatologic Therapy · 2021
    15. Trichotillomania: What Do We Know So Far? Skin appendage disorders · 2021
    16. Patient Recovery from COVID-19 Infections: Follow-Up of Hair, Nail, and Skin Manifestations BioMed Research International · 2021
    17. Cross-Sectional Survey Examining Skin Picking and Hair Pulling Disorders During the COVID-19 Pandemic Journal of The American Academy of Dermatology · 2020
    18. Evaluation of the Effects of COVID-19 Pandemic on Hair Diseases Through a Web-Based Questionnaire Dermatologic Therapy · 2020
    19. Telogen Effluvium: A Review of the Literature Cureus · 2020
    20. Stress-Induced Interaction of Skin Immune Cells, Hormones, and Neurotransmitters Clinical therapeutics · 2020
    21. Topical Minoxidil-Loaded Nanotechnology Strategies for Alopecia Cosmetics · 2020
    22. Acne, the Skin Microbiome, and Antibiotic Treatment American journal of clinical dermatology · 2019
    23. Stress And The Hair Growth Cycle: Cortisol-Induced Hair Growth Disruption PubMed · 2016