Hair Loss in the Elderly

January 2012 in “ Human health handbooks ”

Chia-Han Yang, Antonia Todorova, WenChieh Chen

Studysummary This article reviews hair loss in elderly women, discussing common forms, diagnostic challenges, and the limited effectiveness of current treatments, but presents no new clinical findings.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

We don't know much about this study yet.

View this study on springerlink.com →

Discuss this study in the Community →

Research cited in this study

26 / 26 results

research An Atlas of Hair Pathology with Clinical Correlations

45 citations , May 2012 in “CRC Press eBooks”

The book helps doctors better understand and treat hair disorders due to gaps in their training.

Bald Scalp in Men with Androgenetic Alopecia Retains Hair Follicle Stem Cells but Lacks CD200-Rich and CD34-Positive Hair Follicle Progenitor Cells

research Bald Scalp in Men with Androgenetic Alopecia Retains Hair Follicle Stem Cells but Lacks CD200-Rich and CD34-Positive Hair Follicle Progenitor Cells

235 citations , January 2011 in “Journal of Clinical Investigation”

This study found that androgenetic alopecia may involve a defect in the conversion of hair follicle stem cells to progenitor cells, as demonstrated by a reduced presence of progenitor cells in bald scalp samples.

research Trichoscopy for Common Hair Loss Diseases: Algorithmic Method for Diagnosis

89 citations , December 2010 in “The Journal of Dermatology”

This study describes characteristic trichoscopic features of various hair loss diseases and proposes an algorithmic method for diagnosing them, but reports no new clinical results.

research The Cell Biology of Human Hair Follicle Pigmentation

127 citations , November 2010 in “Pigment cell & melanoma research”

This article discusses the challenges in hair follicle pigmentation research compared to epidermal melanocytes and highlights the limitations of relying on mouse models, but reports no new experimental findings.

research Frontal Fibrosing Alopecia: A Clinical Review of 36 Patients

159 citations , August 2010 in “British journal of dermatology/British journal of dermatology, Supplement”

In this study, hydroxychloroquine significantly reduced signs and symptoms of frontal fibrosing alopecia after 6 months of treatment, with maximal benefits observed within the first 6 months.

research Hair Loss in Elderly Women: A Dermatological Concern

30 citations , March 2010 in “European Journal of Dermatology”

This article discusses hair loss in postmenopausal women as often being multifactorial, reviewing various conditions affecting this group, but reports no new research findings.

research Comparative Gene Expression Profiling of Senescent and Androgenetic Alopecia Using Microarray Analysis

6 citations , January 2010 in “Springer eBooks”

SA linked to mitochondrial issues and oxidative stress, while AGA involves disrupted hair growth genes.

research Review of Hair Follicle Dermal Cells

321 citations , December 2009 in “Journal of Dermatological Science”

This review discusses the role of dermal cells in hair follicle regeneration and morphogenesis and highlights their potential therapeutic implications, but it reports no new empirical findings.

research Hedgehog Signaling Maintains Hair Follicle Stem Cell Phenotype in Young and Aged Human Skin

62 citations , November 2009 in “Aging Cell”

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

research A Case Report of Inflammatory Nonscarring Alopecia Associated with the Epidermal Growth Factor Receptor Inhibitor Erlotinib

33 citations , June 2009 in “Journal of Cutaneous Pathology”

This article discusses the cutaneous side effects of erlotinib, an EGFR inhibitor, in a patient with non-small cell lung cancer, reporting nonscarring alopecia and indicative scalp biopsy findings.

Effect of 1 mg/Day Finasteride on Concentrations of Serum Prostate-Specific Antigen in Men With Androgenic Alopecia: A Randomized Controlled Trial

research Effect of 1 mg/Day Finasteride on Concentrations of Serum Prostate-Specific Antigen in Men With Androgenic Alopecia: A Randomized Controlled Trial

89 citations , December 2006 in “Lancet Oncology”

In this study, 1 mg/day finasteride lowered serum PSA concentration in men aged 40–60, suggesting that PSA adjustment recommendations for prostate cancer screening using 5 mg/day finasteride should also apply to this lower dose for hair loss treatment.

research Revisiting Dandruff: Role of Malassezia Yeasts and Treatment Implications

78 citations , September 2006 in “International Journal of Cosmetic Science”

This paper discusses the role of Malassezia yeast and inflammation in dandruff and highlights the potential of anti-inflammatory antidandruff formulations to improve scalp conditions and hair cycle disturbances; it presents no new experimental results.

research Nonscarring Inflammatory Alopecia Associated With the Epidermal Growth Factor Receptor Inhibitor Gefitinib

57 citations , August 2006 in “Journal of the American Academy of Dermatology”

This case report describes a woman who developed extensive nonscarring inflammatory hair loss after two years of gefitinib treatment, highlighting potential cutaneous side effects associated with epidermal growth factor receptor blockers.

research Frontal Fibrosing Alopecia Versus Lichen Planopilaris: A Clinicopathological Study

126 citations , April 2006 in “International Journal of Dermatology”

This study found that frontal fibrosing alopecia and lichen planopilaris have similar histopathological features, but FFA exhibits more prominent apoptosis and less inflammation with spared interfollicular epidermis.

research The Lack of Significant Changes in Scalp Hair Follicle Density With Advancing Age

33 citations , April 2005 in “British Journal of Dermatology”

This study found that age and follicular miniaturization were extremely weak predictors of total hair count in women with hair loss.

research Treatment of Female Pattern Hair Loss With Oral Antiandrogens

179 citations , March 2005 in “British Journal of Dermatology”

This study found that 88% of women with female pattern hair loss who received oral antiandrogens saw no progression or improvement in their condition.

research Patients With a Large Prostate Show a Higher Prevalence of Androgenetic Alopecia

33 citations , October 2004 in “Archives of Dermatological Research”

This study suggests that a larger prostate is associated with a higher prevalence of androgenetic alopecia, although the prostate size did not correlate with alopecia severity.

research The Reliability of Horizontally Sectioned Scalp Biopsies in the Diagnosis of Chronic Diffuse Telogen Hair Loss in Women

137 citations , July 2004 in “Journal of The American Academy of Dermatology”

This study observed that triple horizontal scalp biopsies provided a more accurate diagnosis of female pattern hair loss in women than a single horizontal biopsy, especially for those with advanced hair loss.

research A Randomized, Placebo-Controlled Trial of 5% and 2% Topical Minoxidil Solutions in the Treatment of Female Pattern Hair Loss

219 citations , March 2004 in “Journal of The American Academy of Dermatology”

In this 48-week trial, 5% topical minoxidil was more effective than both 2% minoxidil and placebo in promoting hair growth in women with female pattern hair loss, with notable improvements in nonvellus hair count and hair growth assessments.

research Finasteride Treatment of Patterned Hair Loss in Normoandrogenic Postmenopausal Women

72 citations , January 2004 in “Dermatology”

This study found that oral finasteride, at a dosage of 2.5 mg/day or more, may improve hair growth and appearance in postmenopausal women with pattern hair loss, without adverse effects.

research Hair Cycle and Hair Pigmentation: Dynamic Interactions and Changes Associated with Aging

152 citations , December 2003 in “Micron”

This review discusses the development, regulation, and aging of the human hair follicle pigmentary system and suggests potential for reversing hair graying by manipulating follicle melanocytes in vitro, but reports no clinical results.

research Lack of Efficacy of Finasteride in Postmenopausal Women with Androgenetic Alopecia

239 citations , November 2000 in “Journal of The American Academy of Dermatology”

In this study, finasteride 1 mg/day for 12 months did not improve hair growth or slow hair thinning in postmenopausal women with androgenetic alopecia compared to placebo.

research Folliculitis Decalvans Including Tufted Folliculitis: Clinical, Histological, and Therapeutic Findings

226 citations , February 1999 in “British Journal of Dermatology”

This study reported that a treatment regimen of oral rifampicin and clindamycin for 10 weeks effectively managed folliculitis decalvans, with most patients experiencing no recurrence after one or multiple courses.

research Expression of a Dominant Negative Mutant of Epidermal Growth Factor Receptor in the Epidermis of Transgenic Mice Elicits Striking Alterations in Hair Follicle Development and Skin Structure.

252 citations , November 1995 in “The EMBO Journal”

Blocking EGFR in mice causes hair loss and skin changes.

research Tinea Capitis in Adults in Southern Taiwan

37 citations , August 1991 in “International Journal of Dermatology”

This study reported a predominance of adult patients, mostly women, with Trichophyton violaceum tinea capitis in southern Taiwan, noting a bimodal age distribution and questioning whether this represents a new trend.

research The Comparative Histopathology of Male-Pattern Baldness and Senescent Baldness

143 citations , October 1988 in “Clinics in Dermatology”

This review discusses the histopathology of male-pattern baldness and highlights ongoing disputes over several aspects, including sebaceous gland size and follicle loss, reporting no new clinical findings.