Promotion of Hair Growth by Traditionally Used Delphinium Staphisagria Seeds Through Induction of Angiogenesis

The study investigated the hair growth-promoting effects of Delphinium staphisagria seeds, traditionally used for hair loss treatment, through in-vitro experiments. Extracts from these seeds were tested on human keratinocytes and endothelial cells to assess cytotoxicity and angiogenic potential. The results showed that vinegar and water extracts significantly increased the proliferation of keratinocyte cells by up to 149% at various concentrations, without causing toxicity. Additionally, the extracts induced angiogenic activity in endothelial cells. These findings suggested that Delphinium staphisagria seeds could promote hair growth by inducing angiogenesis without harmful effects, supporting their traditional use for hair loss.