Promotion of Hair Growth by Traditionally Used Delphinium Staphisagria Seeds Through Induction of Angiogenesis

The study investigated the hair growth-promoting effects of Delphinium staphisagria seeds using in-vitro methods. Extracts from these seeds, traditionally used for treating hair loss, were tested for cytotoxicity and angiogenic potential on human endothelial cells (HUVECs) and keratinocytes (HaCaT). The results showed that vinegar and water extracts significantly increased the proliferation of keratinocyte cells by up to 149% at various concentrations without causing toxicity. Additionally, the extracts induced angiogenic activity, suggesting that D. staphisagria seeds could promote hair growth through angiogenesis without harmful effects, making them a promising candidate for hair growth promotion.