The Therapeutic Role of ADSC-EVs in Skin Regeneration

    June 2022 in “ Frontiers in Medicine ”
    Yixi Wang, Lin Cao, Hanxing Zhao … Zhenyu Zhang
    Studysummary This review discusses the potential of adipose-derived stem cell extracellular vesicles (ADSC-EVs) in skin regeneration, highlighting mechanisms like inflammation and angiogenesis, but reports no new clinical results; challenges and future prospects are also considered.
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    Research cited in this study 14

    1. Adipose-Derived Stem Cell Exosomes Promoted Hair Regeneration Tissue Engineering and Regenerative Medicine · 2021
    2. Human Acellular Amniotic Membrane Incorporating Exosomes from Adipose-Derived Mesenchymal Stem Cells Promotes Diabetic Wound Healing Stem Cell Research & Therapy · 2021
    3. Extracellular Vesicles From Adipose-Derived Stem Cells Ameliorate Ultraviolet B-Induced Skin Photoaging by Attenuating Reactive Oxygen Species Production and Inflammation Stem Cell Research & Therapy · 2020
    4. Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development Cells · 2019
    5. Wound Healing: A Cellular Perspective Physiological Reviews · 2018
    6. Single-Cell Transcriptomics of Traced Epidermal and Hair Follicle Stem Cells Reveals Rapid Adaptations During Wound Healing Cell Reports · 2018
    7. Mesothelial Stem Cells and Stromal Vascular Fraction for Skin Rejuvenation Facial Plastic Surgery Clinics of North America · 2018
    8. Targeting Oxidative Stress and Mitochondrial Dysfunction in the Treatment of Impaired Wound Healing: A Systematic Review Antioxidants · 2018
    9. Serenoa Repens Extracts Promote Hair Regeneration and Repair of Hair Loss in Mouse Models by Activating TGF-β and Mitochondrial Signaling Pathway PubMed · 2018
    10. Hair Growth-Promoting Effect of Geranium Sibiricum Extract in Human Dermal Papilla Cells and C57BL/6 Mice BMC Complementary and Alternative Medicine · 2017
    11. Exosomes for Repair, Regeneration, and Rejuvenation Expert Opinion on Biological Therapy · 2015
    12. Wound Healing and Skin Regeneration Cold Spring Harbor Perspectives in Medicine · 2015
    13. Signaling Involved in Hair Follicle Morphogenesis and Development International Journal of Molecular Sciences · 2014
    14. PDGF Isoforms Induce and Maintain Anagen Phase of Murine Hair Follicles Journal of Dermatological Science · 2006

    Related research 1

    1. Wound Healing and Skin Regeneration Cold Spring Harbor Perspectives in Medicine · 2015