Efficacy of Autologous Platelet-Rich Plasma Combined With a Non-Cross-Linked Hyaluronic Acid Compound in the Treatment of Female Androgenetic Alopecia: A Retrospective, Case-Series Study

June 2023 in “ Journal of Cosmetic Dermatology ”

Shiwei Wang, Dongmei Li, Muyan Zou, Jiaxu Wu, Xuehan Wang, Yu Yang, Xin Li, Wei Yang

platelet-rich plasma non-cross-linked hyaluronic acid androgenetic alopecia hair density hair count alopecia female androgenetic alopecia PRP HA FAGA

TLDR The treatment combining platelet-rich plasma and a non-cross-linked hyaluronic acid compound significantly improved hair density and reduced bald areas in women with androgenetic alopecia, and it's safe with only mild side effects.

The retrospective, case-series study involved 9 female patients with androgenetic alopecia (FAGA) and evaluated the efficacy of a treatment combining autologous platelet-rich plasma (PRP) and a non-cross-linked hyaluronic acid (HA) compound. The treatment led to a significant improvement in hair density and reduction in areas of alopecia, with a 54.51% increase in hair count at 1 month and a 77.25% increase at 3 months. The treatment's clinical efficacy could last beyond 3 months, and patients reported high satisfaction levels. Mild side effects occurred but resolved within 72 hours, and no serious adverse events occurred, indicating the treatment is safe and well-tolerated. The study concluded that the combination of PRP and non-cross-linked HA compound is effective and safe in treating FAGA, but further randomized controlled trials with larger sample sizes are needed to confirm these findings.

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