Clinical manifestations of polycystic ovary syndrome

    January 2024 in “ Medicinska istrazivanja ”
    Radmila Sparić, Jelena Zlatar, Luka Nikolić, Milica Opalić-Palibrk, Lena Radić, Jelica Bjekić-Macut, Sanja Ognjanović, Djuro Μacut
    TLDR PCOS causes hormonal imbalances, irregular periods, and can lead to infertility, obesity, and mental health issues.
    Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age, characterized by hormonal imbalances and diverse clinical presentations, making it difficult to diagnose and manage. Key features include hyperandrogenism, ovulatory dysfunction, and polycystic ovarian morphology, though not all are present in every patient. Hyperandrogenism can lead to hirsutism, acne, and male-pattern alopecia, impacting physical and psychological health. Ovulatory dysfunction causes irregular menstrual cycles and potential infertility. PCOS is often linked with insulin resistance, increasing the risk of obesity, diabetes, and cardiovascular diseases. Additionally, women with PCOS have higher rates of depression and anxiety. The syndrome's complexity and chronic nature necessitate a proactive and comprehensive treatment approach.
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