Chitosan Nanoparticles for Targeting and Sustaining Minoxidil Sulphate Delivery to Hair Follicles

    January 2015 in “ International Journal of Biological Macromolecules ”
    Breno N. Matos, Thaiene Avila Reis, Tais Gratieri
    Studysummary This study developed minoxidil sulphate-loaded chitosan nanoparticles that doubled drug delivery to hair follicles in vitro compared to a control solution, suggesting potential for improved alopecia treatment.
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    Research cited in this study 9

    1. Delivery and Targeting of Nanoparticles into Hair Follicles Therapeutic Delivery · 2014
    2. Squarticles as a Lipid Nanocarrier for Delivering Diphencyprone and Minoxidil to Hair Follicles and Human Dermal Papilla Cells Aaps Journal · 2013
    3. Iontophoresis-Targeted, Follicular Delivery of Minoxidil Sulfate for the Treatment of Alopecia Journal of Pharmaceutical Sciences · 2013
    4. Penetration Enhancer-Containing Vesicles as Carriers for Cutaneous Delivery of Minoxidil: In Vitro Evaluation of Drug Permeation by Infrared Spectroscopy Pharmaceutical Development and Technology · 2012
    5. Chitosan Microparticles for Sustaining the Topical Delivery of Minoxidil Sulphate Journal of Microencapsulation · 2011
    6. Minoxidil Activates β-Catenin Pathway in Human Dermal Papilla Cells: A Possible Explanation for Its Anagen Prolongation Effect Journal of Dermatological Science · 2011
    7. Selective Follicular Targeting by Modification of the Particle Sizes Journal of Controlled Release · 2011
    8. Relative Uptake of Minoxidil Into Appendages and Stratum Corneum and Permeation Through Human Skin In Vitro Journal of Pharmaceutical Sciences · 2009
    9. Transdermal Delivery of Minoxidil with Block Copolymer Nanoparticles Journal of controlled release · 2004