Chitosan nanoparticles for targeting and sustaining minoxidil sulphate delivery to hair follicles
April 2015
in “International Journal of Biological Macromolecules”
TLDR Chitosan nanoparticles improve minoxidil delivery to hair follicles for better alopecia treatment.
The study developed chitosan nanoparticles loaded with minoxidil sulphate (MXS-NP) for targeted delivery to hair follicles, which could sustain drug release and improve the topical treatment of alopecia. The MXS-NP formulation was found to be superior to previously prepared MXS-loaded microparticles in terms of follicular accumulation of MXS and prolonged release of the drug into hair follicles. The study suggests that chitosan nanoparticles could be a promising strategy for the topical treatment of alopecia.
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