Effectiveness and Safety of Baricitinib in Patients With Moderate-to-Severe Refractory Alopecia Areata in Real World: An Open-Label, Single-Center Study

    December 2023 in “ Journal of Cosmetic Dermatology ”
    Lingbo Bi, Chaofan Wang, Yimei Du, Tong Su, Zhao Min, Xuewen Lin, Weifei Fan, Weiyuan Sun
    Image of study
    TLDR Baricitinib effectively and safely improves hair growth in patients with severe alopecia areata.
    The study involved 32 patients with moderate to severe alopecia areata (AA) who were unresponsive to traditional treatments. These patients were treated with baricitinib, a JAK inhibitor, for 24 weeks. The results showed a significant decrease in the Severity of Alopecia Tool (SALT) score from baseline at week 12 and 24, indicating improved hair growth. By the end of the study, 68.75% of patients reported over 80% hair covering of the scalp. Side effects were mild and included transient platelet elevation, elevated transaminase, dizziness, tonsillitis, and acne. The study concluded that baricitinib is effective and safe for treating patients with refractory AA at moderate to severe levels.
    Discuss this study in the Community →

    Research cited in this study

    13 / 13 results

    Related Community Posts Join

    6 / 11 results

      community What else is good. Besides the big 3.

      in Chat  36 upvotes 1 month ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community Should I get transplant #4 or just shave my head?

      in Transplants  169 upvotes 3 months ago
      A 36-year-old considering a fourth hair transplant is advised to either shave his head or use a hair system due to poor results from previous transplants and late medication use. He plans to consult top surgeons and adjust his current treatments, including finasteride and minoxidil.

      community Olumiant active ingredient Baricitinib

      in Research/Science  1 upvotes 1 year ago
      The conversation is about someone inquiring if anyone has tried Olumiant or its active ingredient, Baricitinib, for hair loss, mentioning the cost and that they have ordered Baricitinib.

    Related Research

    1 / 1 results