5 citations
,
February 2019 in “The New England Journal of Medicine” This article discusses the composition and function of the dermal papilla in hair follicles, focusing on its role in hair shaft generation and suggesting that cell loss in this area may contribute to hair loss.
95 citations
,
February 2019 in “The New England Journal of Medicine” This article discusses the potential genetic basis of central centrifugal cicatricial alopecia in women of African ancestry but does not provide new research results.
25 citations
,
October 2018 in “Journal of The American Academy of Dermatology” This study concluded that erosive pustular dermatosis of the scalp may be a type of spongiotic, pustular superficial folliculitis, sharing similarities with other neutrophilic dermatoses.
89 citations
,
August 2018 in “JAMA Dermatology” This study found that the level of expected therapeutic regrowth significantly affected hair regrowth outcomes in contact immunotherapy for alopecia areata, suggesting implications for patient education and adherence.
41 citations
,
June 2018 in “Journal of The American Academy of Dermatology” This study examined the therapeutic response to folliculitis decalvans treatments among 60 patients and found that earlier disease onset was linked to more severe cases, while a combination of rifampicin, clindamycin, tetracyclines, and intralesional steroids was most effective in controlling symptoms.
54 citations
,
May 2018 in “Journal of The European Academy of Dermatology and Venereology” This study found that low-level laser therapy was the most effective non-surgical treatment for androgenetic alopecia, although the overall quality of evidence supporting various therapies was generally low.
74 citations
,
April 2017 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This study classified frontal fibrosing alopecia patients into three clinical patterns, finding that pattern III had the best prognosis and pattern II the worst after treatment with dutasteride and corticosteroids.
53 citations
,
February 2017 in “Journal of The American Academy of Dermatology” In this study of 20 patients with erosive pustular dermatosis of the scalp, using trichoscopy improved diagnosis, and treatments with high-potency steroids or topical tacrolimus effectively reduced inflammatory signs, suggesting these as first-line treatments.
119 citations
,
November 2016 in “American journal of human genetics” This study reports the discovery of mutations in the PADI3, TGM3, and TCHH genes as molecular genetic causes of uncombable hair syndrome in children, indicating an autosomal-recessive inheritance pattern.
65 citations
,
November 2016 in “Journal of The American Academy of Dermatology” This article reviews various types of primary cicatricial alopecias and emphasizes the importance of accurate diagnosis to improve management strategies, particularly detailing remaining lymphocytic forms and expanding on neutrophilic and mixed types.
95 citations
,
November 2016 in “Journal of The American Academy of Dermatology” This article reviews primary cicatricial alopecias, focusing on lymphocytic forms such as chronic cutaneous lupus erythematosus, according to a classification by the North American Hair Research Society, and reports no new clinical results.
238 citations
,
November 2016 in “Journal of The American Academy of Dermatology” In this study, tofacitinib was reported to improve scalp hair regrowth in patients with severe alopecia areata, alopecia totalis, and alopecia universalis, showing a higher response in alopecia areata.
69 citations
,
August 2014 in “Journal of The American Academy of Dermatology” This review discusses recent advances in trichoscopy for differentiating types of alopecia and presents a systematic approach for using its diagnostic findings, but reports no new clinical results.
339 citations
,
February 2014 in “Journal of The American Academy of Dermatology” This study found that eyelash loss, facial papules, and body hair involvement were linked to severe frontal fibrosing alopecia, and antiandrogens were the most effective treatment.
421 citations
,
April 2012 in “The New England Journal of Medicine” Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.
150 citations
,
April 2008 in “Journal of The American Academy of Dermatology” This study found that videodermoscopy reveals distinct dermoscopic features in patients with alopecia areata incognita, aiding in biopsy decisions by identifying the appropriate sampling area and potentially avoiding unnecessary procedures.
10 citations
,
August 2007 in “Journal der Deutschen Dermatologischen Gesellschaft” Individualized treatment plans are crucial for managing excessive hair growth.
304 citations
,
July 2006 in “Journal of The American Academy of Dermatology” This study found that videodermoscopy enhances diagnostic accuracy for scalp and hair disorders beyond simple clinical inspection and reveals novel disease features that could improve clinical understanding.
49 citations
,
September 2004 in “Journal of the European Academy of Dermatology and Venereology” This study found that careful light microscopy using fluid-mounted hair improves detection of the pili annulati phenotype, which varies widely in expression and affects hair fragility.
72 citations
,
November 2000 in “Archives of Dermatology” This study found that excision with primary closure is an effective surgical treatment for extensive acne keloidalis nuchae, with good cosmetic results and minimal recurrence observed among patients.
36 citations
,
October 2000 in “British Journal of Dermatology” This study identified a distinct gene near the hairless locus on chromosome 8p that is responsible for hereditary Marie Unna type hypotrichosis in a German family.
1113 citations
,
August 1999 in “The New England Journal of Medicine” This article discusses the biologic and psychosocial significance of hair, the current limitations in hair growth drugs, and anticipates future therapies based on advancing hair follicle research.
226 citations
,
February 1999 in “British Journal of Dermatology” This study reported that a treatment regimen of oral rifampicin and clindamycin for 10 weeks effectively managed folliculitis decalvans, with most patients experiencing no recurrence after one or multiple courses.
412 citations
,
January 1998 in “Science” This study identified a missense mutation in the human hairless gene associated with a rare form of recessively inherited alopecia universalis, pinpointed on chromosome 8p12.
329 citations
,
January 1997 in “Journal of the American Academy of Dermatology” This study reports that progressive frontal fibrosing alopecia, a distinct and gradually stabilizing form of lichen planopilaris affecting elderly women and often involving eyebrow hair loss, lacks effective treatments.
234 citations
,
December 1996 in “Journal of The American Academy of Dermatology” The authors concluded that chronic telogen effluvium in middle-aged women presents distinct clinical and histological features that differ from androgenetic alopecia and acute telogen effluvium.
325 citations
,
June 1994 in “Archives of Dermatology” This study observed that progressive frontal recession in postmenopausal women may exhibit features of fibrosing alopecia, suggesting a distinct reaction pattern from typical lichen planopilaris.
85 citations
,
February 1989 in “Journal of The American Academy of Dermatology” This case report describes a newly identified condition called loose anagen hair of childhood, characterized by easily pluckable hair in two young boys, with variable duration and no scalp inflammation or scarring.
31 citations
,
November 1986 in “Journal of the American Academy of Dermatology” 203 citations
,
November 1984 in “Journal of the American Academy of Dermatology” This study presents evidence suggesting that androgenetic alopecia is most likely inherited through a polygenic model, challenging the traditional view that it is caused by a simple Mendelian autosomal dominant gene.
175 citations
,
December 1980 in “Archives of Dermatology” In this study, researchers examined two new cases of trichothiodystrophy and observed that the condition is linked to decreased synthesis of high-sulfur matrix proteins in hair.
666 citations
,
September 1977 in “British Journal of Dermatology” This article presents a classification system for stages of female-pattern androgenetic alopecia to aid early diagnosis and mentions existing systems for rare male-pattern cases, but reports no new clinical results.