Therapeutic Considerations Related to Finasteride Administration in Male Androgenic Alopecia and Benign Prostatic Hyperplasia

    January 2017 in “ Farmacia ”
    Ion G. Motofei, David L. Rowland, Daniela Luiza Baconi … Ioanel Sinescu
    Studysummary This review discusses the safety of finasteride for male androgenic alopecia and benign prostatic hyperplasia, concluding it remains a viable option due to synergistic effects with other treatments and predictive measures for side effect risk.
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    Research cited in this study 21

    1. Informational Dichotomy of the Mind: The Role of Sexual Neuromodulators Journal of Mind and Medical Sciences · 2017
    2. Differences in Reproductive Toxicology Between Alopecia Drugs: An Analysis on Adverse Events Among Female and Male Cases Oncotarget · 2016
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    5. Finasteride Adverse Effects in Subjects with Androgenic Alopecia: A Possible Therapeutic Approach According to the Lateralization Process of the Brain Journal of Dermatological Treatment · 2016
    6. Long-Term Safety and Efficacy of Dutasteride in the Treatment of Male Patients with Androgenetic Alopecia Journal of Dermatology · 2016
    7. An Observational Retrospective Evaluation of 79 Young Men with Long-Term Adverse Effects After Use of Finasteride Against Androgenetic Alopecia International Journal of Andrology · 2016
    8. Finasteride Side Effects and Post-Finasteride Syndrome in Male Androgenic Alopecia Journal of Mind and Medical Sciences · 2015
    9. Persistent Sexual Dysfunction and Suicidal Ideation in Young Men Treated with Low-Dose Finasteride: A Pharmacovigilance Study Pharmacotherapy · 2015
    10. Combined Treatment with Oral Finasteride and Topical Minoxidil in Male Androgenetic Alopecia: A Randomized and Comparative Study in Chinese Patients Dermatologic Therapy · 2015
    11. Safety Concerns Regarding 5α Reductase Inhibitors for the Treatment of Androgenetic Alopecia Current Opinion in Endocrinology, Diabetes and Obesity · 2015
    12. Patients Treated for Male Pattern Hair Loss with Finasteride Show Altered Levels of Neuroactive Steroids in Cerebrospinal Fluid and Plasma After Discontinuation The Journal of Steroid Biochemistry and Molecular Biology · 2014
    13. Persistent Sexual and Nonsexual Adverse Effects of Finasteride in Younger Men Sexual medicine reviews · 2013
    14. The Efficacy and Safety of 5α-Reductase Inhibitors in Androgenetic Alopecia: A Network Meta-Analysis and Benefit–Risk Assessment of Finasteride and Dutasteride Journal of Dermatological Treatment · 2013
    15. A Pilot Study on the Sexual Side Effects of Finasteride as Related to Hand Preference for Men Undergoing Treatment of Male Pattern Baldness BJUI · 2012
    16. Depressive Symptoms and Suicidal Thoughts Among Former Users of Finasteride With Persistent Sexual Side Effects The Journal of Clinical Psychiatry · 2012
    17. Finasteride and Male Breast Cancer: Does the MHRA Report Show a Link? PubMed · 2010
    18. Saturable Binding of Finasteride to Steroid 5α-Reductase as Determinant of Nonlinear Pharmacokinetics Drug Metabolism and Pharmacokinetics · 2010
    19. Finasteride in the Treatment of Patients with Benign Prostatic Hyperplasia: A Review Therapeutics and Clinical Risk Management · 2009
    20. Follow-Up of 1 mg Finasteride Treatment of Male Pattern Baldness: Differences Between Clinical Trials and Private Office Follow-Up and Influences on Prescribing Habits Evaluated Dermatologic Surgery · 2004
    21. Finasteride, a Type 2 5α-Reductase Inhibitor, in the Treatment of Men with Androgenetic Alopecia Expert Opinion on Investigational Drugs · 1999

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    2. Adverse Effects of 5-Alpha Reductase Inhibitor Therapy in Men With Androgenetic Alopecia: Is There Cause for Concern? Actas Dermo-Sifiliográficas · 2016
    3. Male Alopecia, Finasteride, and Cancer Risk Community oncology · 2012
    4. Therapeutic Hotline: Treatment of Androgenic Alopecia with Finasteride May Result in High-Grade Prostate Cancer in Patients: Fact or Fiction? Dermatologic Therapy · 2010
    5. Finasteride for Prostatic Disease: An Updated and Comprehensive Review Expert opinion on drug metabolism & toxicology · 2008
    6. Why Would Men Use Finasteride in 2005? Current Prostate Reports · 2005
    7. Novel Inhibitors of 5α-Reductase Expert Opinion on Therapeutic Patents · 2002
    8. Selections from Current Literature: Androgenetic Alopecia - The Science Behind a New Oral Treatment Family Practice · 1998