Multistage Transdermal Nitric Oxide Delivery System for the Efficient Treatment of Androgenic Alopecia

    November 2024 in “ ACS Materials Letters ”
    Hui Xing, Xinlin Jiang, Ziyi Zhao … Dong Ma
    Studysummary This study developed a nitric oxide delivery system using PVA films and HA liposomes, which enhanced hair follicle vitality and repaired blood vessels in androgenic alopecia by promoting angiogenesis and reducing inflammation through the HIF-1 signaling pathway.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on doi.org →
    Discuss this study in the Community →

    Research cited in this study 11

    1. Nitric Oxide Synergizes Minoxidil Delivered by Transdermal Hyaluronic Acid Liposomes for Multimodal Androgenetic Alopecia Therapy Bioactive Materials · 2023
    2. Nitric Oxide: Physiological Functions, Delivery, and Biomedical Applications Advanced Science · 2023
    3. Platelet Lysate Promotes Hair Growth: In Vitro and In Vivo Mechanism and Randomized, Controlled Trial Biomedicine & pharmacotherapy · 2023
    4. Androgen Receptor-Mediated Paracrine Signaling Induces Regression of Blood Vessels in the Dermal Papilla in Androgenetic Alopecia Journal of Investigative Dermatology · 2022
    5. Comparative Histological and Immunohistochemical Study on the Effect of Platelet-Rich Plasma and Minoxidil, Alone or in Combination, on Hair Growth in a Rat Model of Androgenic Alopecia Tissue & Cell · 2022
    6. Functional Hair Follicle Regeneration: An Updated Review Signal Transduction and Targeted Therapy · 2021
    7. Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil, Finasteride, and Adult Stem Cell-Based Therapy International Journal of Molecular Sciences · 2020
    8. 3-Deoxysappanchalcone Promotes Proliferation of Human Hair Follicle Dermal Papilla Cells and Hair Growth in C57BL/6 Mice by Modulating WNT/β-Catenin and STAT Signaling Biomolecules & Therapeutics · 2016
    9. Liposomal Systems as Drug Delivery Vehicles for Dermal and Transdermal Applications Archives of Dermatological Research · 2011
    10. Androgenetic Alopecia: Clinical Features, Classification, and Treatments Endocrinology and Metabolism Clinics of North America · 2007
    11. Effect of Minoxidil on Proliferation and Apoptosis in Dermal Papilla Cells of Human Hair Follicle Journal of Dermatological Science · 2004