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    Effects of Oxytocin Receptor Agonists on Hair Growth Promotion

    October 2024 in “ Scientific Reports ”
    Tatsuto Kageyama, Jieun Seo, Lei Yan, Junji Fukuda
    Studysummary This research observed that oxytocin receptor agonists WAY267464 and LIT001 increased hair growth-related gene expression in human dermal papilla cells and significantly promoted hair follicle sprouting in vitro, suggesting their potential as hair growth agents targeting OXTR for alopecia treatment.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 16

    1. Effects of Oxytocin on the Hair Growth Ability of Dermal Papilla Cells Scientific Reports · 2023
    2. Clinical Outcomes for Uptitration of Baricitinib Therapy in Patients With Severe Alopecia Areata JAMA Dermatology · 2023
    3. Janus Kinase Inhibitors For Alopecia Areata JAMA network open · 2023
    4. In Vitro Hair Follicle Growth Model for Drug Testing Scientific Reports · 2023
    5. Efficacy of Asymmetric siRNA Targeting Androgen Receptors for the Treatment of Androgenetic Alopecia Molecular Pharmaceutics · 2022
    6. Impacts of Manipulating Cell Sorting on In Vitro Hair Follicle Regeneration Journal of Bioscience and Bioengineering · 2022
    7. Co-Delivery of Bioactive Peptides by Nanoliposomes for Promotion of Hair Growth Journal of Drug Delivery Science and Technology · 2022
    8. Weekly Treatment with SAMiRNA Targeting the Androgen Receptor Ameliorates Androgenetic Alopecia Scientific Reports · 2022
    9. Finasteride for Hair Loss: A Review Journal of Dermatological Treatment · 2021
    10. Hair Growth Is Promoted by BeauTop via Expression of EGF and FGF-7 Molecular Medicine Reports · 2018
    11. Dutasteride in Androgenetic Alopecia: An Update Current Clinical Pharmacology · 2017
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    13. Minoxidil Use in Dermatology, Side Effects, and Recent Patents Recent Patents on Inflammation & Allergy Drug Discovery · 2012
    14. Minoxidil Activates β-Catenin Pathway in Human Dermal Papilla Cells: A Possible Explanation for Its Anagen Prolongation Effect Journal of Dermatological Science · 2011
    15. Effect of Minoxidil on Proliferation and Apoptosis in Dermal Papilla Cells of Human Hair Follicle Journal of Dermatological Science · 2004
    16. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002