Integrated Single-Cell Analysis Reveals Spatially and Temporally Dynamic Heterogeneity in Fibroblast States During Wound Healing

    July 2024 in “ Journal of Investigative Dermatology ”
    Axel A. Almet, Yingzi Liu, Qing Nie, Maksim V. Plikus
    Studysummary This study used single-cell RNA-sequencing data from mouse skin to reveal that fibroblasts show high transcriptional plasticity during wound healing, forming transient microniches early on and stratifying scar tissue into distinct molecular layers over time.
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    Research cited in this study 15

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