Akt2 and SGK3 Are Both Determinants of Postnatal Hair Follicle Development

    May 2009 in “ The FASEB Journal ”
    Theodora M. Mauro, James A. McCormick, Jian Wang … David Pearce
    Studysummary This study found that Akt2 and SGK3 are crucial for postnatal hair follicle development in mice, as their combined absence led to severe hair growth defects due to disrupted β-catenin-dependent transcriptional processes.
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    Research cited in this study 10

    1. Vitamin D Receptor Is Essential For Normal Keratinocyte Stem Cell Function Proceedings of the National Academy of Sciences · 2007
    2. The Critical Roles of Serum/Glucocorticoid-Regulated Kinase 3 (SGK3) in Hair Follicle Morphogenesis and Homeostasis American Journal of Pathology · 2006
    3. Development and Progression of Alopecia in the Vitamin D Receptor Null Mouse Journal of cellular physiology · 2006
    4. Sgk3 Links Growth Factor Signaling to Maintenance of Progenitor Cells in the Hair Follicle The Journal of Cell Biology · 2005
    5. Bone Morphogenetic Protein Signaling Controls Hair Pigmentation Through Cross-Talk With the Melanocortin Receptor-1 Pathway Proceedings of the National Academy of Sciences · 2004
    6. Bone Morphogenetic Protein Signaling Regulates Postnatal Hair Follicle Differentiation and Cycling ˜The œAmerican journal of pathology · 2004
    7. P53 Involvement in the Control of Murine Hair Follicle Regression American Journal of Pathology · 2001
    8. Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells Cell · 2001
    9. A Role for p75 Neurotrophin Receptor in the Control of Apoptosis-Driven Hair Follicle Regression The FASEB Journal · 2000
    10. Multiple Roles for Activated LEF/TCF Transcription Complexes During Hair Follicle Development and Differentiation Development · 1999