The Bright Side of Fibroblasts: Molecular Signature and Regenerative Cues in Major Organs

    August 2021 in “ npj Regenerative Medicine ”
    Rita N. Gomes, Filipa Manuel, Diana S. Nascimento
    Studysummary This review examines how fibroblasts contribute to regeneration in various organs and explores the potential of reverting adult fibroblasts to a fetal-like state for regenerative therapies, but reports no new empirical findings.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 19

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    9. Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations Journal of Investigative Dermatology · 2018
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    12. Dermal Blimp1 Acts Downstream of Epidermal TGFβ and Wnt/β-Catenin to Regulate Hair Follicle Formation and Growth Journal of Investigative Dermatology · 2017
    13. Activating Beta-Catenin Signaling in CD133-Positive Dermal Papilla Cells Increases Hair Inductivity FEBS Journal · 2016
    14. Inhibition of β-Catenin Signaling in Dermal Fibroblasts Enhances Hair Follicle Regeneration During Wound Healing Development · 2016
    15. Wound Healing and Skin Regeneration Cold Spring Harbor Perspectives in Medicine · 2015
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    19. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007

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    1. The Bright Side of Fibroblasts: Molecular Signature and Regenerative Cues in Major Organs npj Regenerative Medicine · 2021