Intermediate Hair Follicles: A New, More Clinically Relevant Model for Hair Growth Investigations

    Benjamin H. Miranda, Desmond J. Tobin, David T. Sharpe, Valerie A. Randall
    Studysummary This study found that intermediate hair follicles are morphologically distinct from terminal follicles and offer a novel model for developing new alopecia therapies despite being technically more challenging to study.
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    Research cited in this study 22

    1. From Telogen to Exogen: Mechanisms Underlying Formation and Subsequent Loss of the Hair Club Fiber Journal of Investigative Dermatology · 2009
    2. Alopecia Areata: Evidence-Based Treatments Seminars in cutaneous medicine and surgery · 2009
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    4. Androgens and Hair Growth Dermatologic Therapy · 2008
    5. Human Hair Follicles Contain Two Forms of ATP-Sensitive Potassium Channels, Only One Sensitive to Minoxidil The FASEB Journal · 2008
    6. Hormonal Regulation of Hair Follicles Exhibits a Biological Paradox Seminars in Cell & Developmental Biology · 2007
    7. Unwanted Facial Hair: Effects and Solutions Dermatology · 2007
    8. Limitations of Human Occipital Scalp Hair Follicle Organ Culture for Studying the Effects of Minoxidil as a Hair Growth Enhancer Experimental Dermatology · 2004
    9. Burden of Hair Loss: Stress and the Underestimated Psychosocial Impact of Telogen Effluvium and Androgenetic Alopecia Journal of Investigative Dermatology · 2004
    10. Effect of Minoxidil on Proliferation and Apoptosis in Dermal Papilla Cells of Human Hair Follicle Journal of Dermatological Science · 2004
    11. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    12. Animal and In Vitro Models for the Study of Hair Follicles Journal of Investigative Dermatology Symposium Proceedings · 2003
    13. Plasticity and Cytokinetic Dynamics of the Hair Follicle Mesenchyme: Implications for Hair Growth Control Journal of Investigative Dermatology · 2003
    14. Possible Mechanisms of Miniaturization During Androgenetic Alopecia or Pattern Hair Loss Journal of The American Academy of Dermatology · 2001
    15. Differences in Hair Follicle Dermal Papilla Volume Are Due to Extracellular Matrix Volume and Cell Number: Implications for the Control of Hair Follicle Size and Androgen Responses Journal of Investigative Dermatology · 1999
    16. Measuring Reversal of Hair Miniaturization in Androgenetic Alopecia by Follicular Counts in Horizontal Sections of Serial Scalp Biopsies: Results of Finasteride 1mg Treatment of Men and Postmenopausal Women Journal of Investigative Dermatology Symposium Proceedings · 1999
    17. Effects of Self-Perceived Hair Loss in a Community Sample of Men Dermatology · 1998
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    19. Psychological Effects of Androgenetic Alopecia on Women: Comparisons with Balding Men and Female Control Subjects Journal of The American Academy of Dermatology · 1993
    20. The Psychological Effects of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 1992
    21. Human Hair Growth In Vitro Journal of Cell Science · 1990
    22. Studies on the Biochemistry and Morphology of Freshly Isolated and Maintained Rat Hair Follicles Journal of Cell Science · 1989

    Related research 6

    1. Hair Loss (Alopecia or Baldness) 2018
    2. Treatments of Hereditary Hair Loss (Alopecia) 2018
    3. Hair Regrowth in Male and Female Pattern Hair Loss Does Not Involve the Conversion of Vellus Hair to Terminal Hair Experimental Dermatology · 2016
    4. Intermediate Hair Follicles: A New, More Clinically Relevant Model for Hair Growth Investigations British Journal of Dermatology · 2010
    5. Androgens and Hair Growth Dermatologic Therapy · 2008
    6. Disorders of Hair Growth: Diagnosis and Treatment McGraw-Hill eBooks · 1994