Role of the Soluble Epoxide Hydrolase in Hair Follicle Stem Cell Homeostasis and Hair Growth

    June 2022 in “ Pflügers Archiv - European Journal of Physiology ”
    Zumer Naeem, Sven Zukunft, Stephan Günther … Ingrid Fleming
    Studysummary This study found that the deletion of soluble epoxide hydrolase (sEH) in mice altered the hair follicle cycle and increased hair growth through effects on hair follicle stem and matrix cells.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on link.springer.com →
    Discuss this study in the Community →

    Research cited in this study 15

    1. Activation of Hair Cell Growth Factors by Linoleic Acid in Malva Verticillata Seed Molecules/Molecules online/Molecules annual · 2021
    2. Phosphodiesterase Inhibitors and Prostaglandin Analogues in Dermatology: A Comprehensive Review Dermatologic Therapy · 2020
    3. New Drugs Under Investigation for the Treatment of Alopecias Expert Opinion on Investigational Drugs · 2019
    4. Regulation of Melanocyte Stem Cells in the Pigmentation of Skin and Its Appendages: Biological Patterning and Therapeutic Potentials Experimental Dermatology · 2018
    5. Annurca Apple Polyphenols Protect Murine Hair Follicles from Taxane-Induced Dystrophy and Redirect Polyunsaturated Fatty Acid Metabolism Toward β-Oxidation Nutrients · 2018
    6. Mobilizing Transit-Amplifying Cell-Derived Ectopic Progenitors Prevents Hair Loss from Chemotherapy or Radiation Therapy Cancer Research · 2017
    7. Epithelial-Mesenchymal Micro-Niches Govern Stem Cell Lineage Choices Cell · 2017
    8. Role of Arachidonic Acid in Promoting Hair Growth Annals of dermatology/Annals of Dermatology · 2016
    9. Effect of a Nutritional Supplement on Hair Loss in Women Journal of Cosmetic Dermatology · 2015
    10. Cutaneous Retinoic Acid Levels Determine Hair Follicle Development And Downgrowth Journal of biological chemistry/˜The œJournal of biological chemistry · 2012
    11. Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration Cell · 2011
    12. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001
    13. Multiple Roles for Activated LEF/TCF Transcription Complexes During Hair Follicle Development and Differentiation Development · 1999
    14. Induction of the Hair Growth Phase in Postnatal Mice by Localized Transient Expression of Sonic Hedgehog Journal of Clinical Investigation · 1999
    15. The Secret Life of the Hair Follicle Trends in genetics · 1992

    Related research 3

    1. Dynamic Wnt5a Expression in Murine Hair Follicle Cycle and Its Inhibitory Effects on Follicular Growth Asian Pacific journal of tropical medicine · 2014
    2. Epithelial Wnt Ligand Secretion Is Required for Adult Hair Follicle Growth and Regeneration Journal of Investigative Dermatology · 2012
    3. Beta-Catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair Developmental Cell · 2010