Investigation of the Cutaneous Penetration Behavior of Dexamethasone Loaded to Nano-Sized Lipid Particles by EPR Spectroscopy, and Confocal Raman and Laser Scanning Microscopy

    December 2016 in “ European journal of pharmaceutics and biopharmaceutics ”
    Silke B. Lohan, Siavash Saeidpour, Agnieszka Solik … Martina C. Meinke
    Studysummary This study found that nano-sized lipid particles improved the skin accumulation and retention of dexamethasone compared to a base cream, suggesting potential benefits for inflammatory skin disease treatment.
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    Research cited in this study 4

    1. Penetration of Silver Nanoparticles Into Porcine Skin Ex Vivo Using Fluorescence Lifetime Imaging Microscopy, Raman Microscopy, and Surface-Enhanced Raman Scattering Microscopy Journal of Biomedical Optics · 2014
    2. Selective Follicular Targeting by Modification of the Particle Sizes Journal of Controlled Release · 2011
    3. Differential Stripping: Determination of the Amount of Topically Applied Substances Penetrated into the Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005
    4. Variations of Hair Follicle Size and Distribution in Different Body Sites Journal of Investigative Dermatology · 2004