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GlossaryLipid Nanoparticles

tiny, fat-based carriers used to deliver drugs into cells

Lipid Nanoparticles (LNPs) are tiny, spherical particles made from lipids, which are fat-like molecules. They are used to deliver drugs, including genetic material like mRNA, directly into cells. This technology is crucial in modern medicine, such as in the development of mRNA vaccines for COVID-19, because it protects the therapeutic material and ensures it reaches the target cells effectively.

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Investigation of the Cutaneous Penetration Behavior of Dexamethasone Loaded to Nano-Sized Lipid Particles by EPR Spectroscopy, and Confocal Raman and Laser Scanning Microscopy

research Investigation of the Cutaneous Penetration Behavior of Dexamethasone Loaded to Nano-Sized Lipid Particles by EPR Spectroscopy, and Confocal Raman and Laser Scanning Microscopy

21 citations, December 2016 in “European journal of pharmaceutics and biopharmaceutics”

Nano-sized lipid particles increase dexamethasone's skin penetration and create a reservoir in the skin layers.

research Nanostructured Lipid Carrier for Topical Application of N-Acetyl Glucosamine

15 citations, December 2016 in “Advanced Pharmaceutical Bulletin”

The new cream with N-acetyl glucosamine didn't change skin color after 8 weeks.

research Nanotechnology Advances for Hair Loss

27 citations, August 2018 in “Therapeutic Delivery”

Nanotechnology could make hair loss treatments more effective and reduce side effects, but more research is needed before it's available.

research Methodologies to Evaluate the Hair Follicle-Targeted Drug Delivery Provided by Nanoparticles

4 citations, July 2023 in “Pharmaceutics (Basel)”

Nanoparticle-based drug delivery to hair follicles is more effective when tested under conditions that match skin behavior.

research Inhaled Medicines for Targeting Non-Small Cell Lung Cancer

2 citations, December 2023 in “Pharmaceutics”

Inhaling medicine may reduce side effects and improve treatment for a major lung cancer type.

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community to all people who cannot tolerate anti androgens (loe dose topical fin, pyrilutamide, CB) i am getting desperate, looking for a solution

in Research/Science 13 upvotes 1 year ago

The user tried Minoxidil without success, and Finasteride worked but caused sexual side effects even at a very low dose. They are seeking alternative treatments for hair loss as they cannot tolerate anti-androgens and are also in therapy for mental health.

community Fats on your Head to Stop Hair Loss?

in Research/Science 141 upvotes 9 months ago

The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

community Lion Mane Part 2: Microneedling with Topicals, beneficial compounds, maybe?

in Microneedling 1 upvotes 6 months ago

The conversation discusses microneedling techniques and the use of Minoxidil, copper peptides, EGF, FGF, ceramides, and hydration serums to enhance hair growth. It explores optimizing scalp conditions and the potential benefits of various compounds in conjunction with microneedling.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

in Research/Science 73 upvotes 4 months ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community No results with medications, now in contact with restoration clinic. Looking for advice on options - including facial hair.

in Transplants 3 upvotes 7 months ago

The individual has experienced no hair regrowth from using minoxidil and finasteride and is considering a hair restoration clinic's options, including PRP and nano follicle hair replacement, as well as a potential beard transplant. They are seeking advice on whether to pursue PRP, timing for hair replacement surgery, and experiences with beard transplants.

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