November 201819
Scalp micropigmentation for advanced baldness achieved near-perfect satisfaction scores in patients with extensive hair loss. Two sessions of platelet-rich plasma improved hair density and the terminal-to-vellus ratio in pattern hair loss patients. Non-shaven follicular unit extraction avoided donor-area shaving while maintaining a low transection rate. Finasteride in pattern hair loss raised total hair count without reducing vellus hairs, suggesting empty kenogen follicles drive visible rarefaction. Apremilast for alopecia areata showed no benefit over placebo in a randomized trial.
- Shaved hair style scalp medical tattooing technique for treatment of advanced male pattern baldness patients. Scalp micropigmentation giving a shaved-head look achieved near-perfect satisfaction scores in 80 patients with advanced baldness.
- Efficacy of platelet-rich plasma in androgenetic alopecia patients Two PRP injection sessions improved hair density and terminal-to-vellus ratio over six months in 30 pattern hair loss patients.
- Treatment of female pattern hair loss with combination therapy A review outlines how female pattern hair loss often needs combinations of topical, systemic and procedural treatments.
- Annurca Apple Polyphenols Protect Murine Hair Follicles from Taxane Induced Dystrophy and Hijacks Polyunsaturated Fatty Acid Metabolism toward β-Oxidation Annurca apple polyphenols protected mouse hair follicles from taxane damage in vitro, suggesting a chemotherapy-compatible option for chemo hair loss.
- Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing Activating Sonic hedgehog signaling created inductive dermis that regenerated hair follicles in healing mouse wounds instead of scars.
- A randomized placebo-controlled single-center pilot study of the safety and efficacy of apremilast in subjects with moderate-to-severe alopecia areata In a 30-patient trial, apremilast showed no benefit over placebo for moderate-to-severe alopecia areata.
- Nonshaven Follicular Unit Extraction Non-shaven FUE in 658 patients averaged 8.2% transection and avoided donor-area shaving, appealing for those unwilling to shave.
- Treatment of alopecia areata: An Australian expert consensus statement An Australian expert consensus proposes a treatment algorithm for alopecia areata, including when to start and stop systemic therapies.
- The Higher Number and Longer Duration of Kenogen Hairs Are the Main Cause of the Hair Rarefaction in Androgenetic Alopecia. Finasteride raised total hair count 55% without reducing vellus hairs; the authors propose empty kenogen follicles drive visible rarefaction.
- Acne development in male androgenetic alopecia examines acne development in men with androgenetic alopecia.
- Response to tofacitinib therapy of eyebrows and eyelashes in alopecia areata reports eyebrow and eyelash regrowth with tofacitinib in alopecia areata.
- Frontal fibrosing alopecia: a case series of 65 patients seen in a single Italian centre In 65 Italian FFA patients, eyebrow loss could precede hair loss and treatment arrested progression in 75%.
- Facial and Extrafacial Lesions in an Ethnically Diverse Series of 91 Patients with Frontal Fibrosing Alopecia Followed at a Single Center In 91 frontal fibrosing alopecia patients, facial papules clustered with Hispanic ethnicity and premenopausal status, possibly marking severer disease.
- Familial frontal fibrosing alopecia: A cross‐sectional study of 20 cases from nine families Twenty familial frontal fibrosing alopecia cases support a genetic component, with daughters developing disease earlier than affected mothers.
- Examination of Fluconazole-Induced Alopecia in an Animal Model and Human Cohort Fluconazole caused telogen effluvium in both rats and patients; retinoic acid levels were not responsible.
- <i>Serenoa repens</i> and <i>N</i>‐acetyl glucosamine/milk proteins complex differentially affect the paracrine communication between endothelial and follicle dermal papilla cells In cell cultures, saw palmetto and a milk-protein complex altered growth factor and 5-alpha-reductase signaling in follicle-supporting cells.
- Impact on Quality of Life in Patients who came with Androgenetic Alopecia for Hair Transplantion Surgery in a Clinic. In 120 hair transplant candidates, androgenetic alopecia had a small average impact on quality of life, mainly self-consciousness.
- HrQoL in hair loss‐affected patients with alopecia areata, androgenetic alopecia and telogen effluvium: the role of personality traits and psychosocial anxiety Women with androgenetic alopecia reported more anxiety and quality-of-life impact than men; anxiety traits predicted burden regardless of severity.
- The Medical and Psychosocial Associations of Alopecia: Recognizing Hair Loss as More Than a Cosmetic Concern A review links alopecia to thyroid disease, diabetes, depression and reduced quality of life, urging medical rather than cosmetic framing.