February 201815
FUE hair transplantation in 152 patients reported forehead swelling in 70% and temporary shedding in 43%, though 86% reported excellent one-year results. Intradermal growth-factor injections in 1000 patients cut hair fall in 83% and raised hair count at one year. Oral finasteride 2.5 mg in women improved hair in 95%, working better with milder loss and later onset. PRP scalp injections in ten patients increased hair shaft diameter by about 40% after six months. Carboxytherapy in 80 patients improved pattern hair loss density versus placebo, with partial regression on follow-up. Oral tofacitinib in alopecia areata produced at least 50% regrowth in eight of twelve patients.
- Clinical Outcome and Safety Profile of Patients Underwent Hair Transplantation Surgery by Follicular Unit Extraction In 152 FUE hair transplant patients, forehead swelling occurred in 70% and temporary shedding in 43%, with 86% reporting excellent one-year results.
- Intradermal injections of a hair growth factor formulation for enhancement of human hair regrowth – safety and efficacy evaluation in a first-in-man pilot clinical study In an open-label pilot of 1000 patients, eight sessions of injected growth factors cut hair fall in 83% and raised hair count at one year.
- Clinical efficacy of oral administration of finasteride at a dose of 2.5 mg/day in women with female pattern hair loss In 112 women with pattern hair loss, daily finasteride 2.5 mg improved hair in 95%, working better with milder loss and later onset.
- Effect of platelets‐rich plasma on scalp hair diameter In ten patients, three PRP scalp injections increased hair shaft diameter by about 40% after six months.
- Study of the efficacy of carboxytherapy in alopecia In 80 patients, carboxytherapy improved alopecia areata scores and pattern hair loss density versus placebo, with partial regression on follow-up.
- An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch-Type Alopecia Areata, Totalis, and Universalis In 12 patients with moderate-to-severe alopecia areata, oral tofacitinib produced at least 50% hair regrowth in eight, with minimal adverse events.
- Patient-reported outcome assessment and objective evaluation of chemotherapy-induced alopecia In chemotherapy-induced alopecia, objective Hair Check measurement did not match patient reports; patient opinion best assessed hair loss.
- Effect of<i>Cinnamomum osmophloeum</i>Kanehira Leaf Aqueous Extract on Dermal Papilla Cell Proliferation and Hair Growth Cinnamon leaf extract promoted dermal papilla cell proliferation in vitro and hair growth in depilated mice.
- Minoxidil Promotes Hair Growth through Stimulation of Growth Factor Release from Adipose-Derived Stem Cells In mice, minoxidil-treated fat stem cells released growth factors that accelerated hair growth and boosted minoxidil's effect.
- Mechanism of action of minoxidil in the treatment of androgenetic alopecia is likely mediated by mitochondrial adenosine triphosphate synthase-induced stem cell differentiation. A hypothesis paper proposes minoxidil grows hair by driving calcium-triggered stem cell differentiation via ATP synthase.
- Activation of Wnt/β-catenin signaling is involved in hair growth-promoting effect of 655-nm red light and LED in in vitro culture model In cultured human follicles, 655-nm red light elongated hair shafts and delayed catagen via Wnt/β-catenin activation.
- Minoxidil-encapsulated poly(L-lactide-co-glycolide) nanoparticles with hair follicle delivery properties prepared using W/O/W solvent evaporation and sonication Minoxidil-loaded nanoparticles delivered 2.5 times more drug into mouse hair follicles than plain solution.
- In vivo evaluation of insect wax for hair growth potential In mice, insect wax promoted hair regrowth comparable to 5% minoxidil by shifting follicles into the growth phase.
- Peroxisome Proliferator–Activated Receptor-γ−Mediated Signaling Regulates Mitochondrial Energy Metabolism in Human Hair Follicle Epithelium PPAR-gamma signaling regulates mitochondrial energy metabolism in human hair follicle epithelium.
- Rethinking biotin therapy for hair, nail, and skin disorders a piece rethinking the use of biotin therapy for hair, nail, and skin disorders.