TNF-Inhibitor Associated Psoriatic Alopecia: Diagnostic Utility of Sebaceous Lobule Atrophy

    March 2017 in “ Journal of cutaneous pathology ”
    Olga K. Afanasiev, Cathryn Z. Zhang, Steven M. Ruhoy
    Studysummary This study describes tumor necrosis factor inhibitor-associated psoriatic alopecia, highlighting the distinctive histologic feature of sebaceous lobule atrophy, which is potentially reversible and helps differentiate it from idiopathic psoriatic alopecia.
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    Research cited in this study 10

    1. Sebocytes Differentially Express and Secrete Adipokines Experimental Dermatology · 2015
    2. Psoriatic Alopecia Clinical and Experimental Dermatology · 2015
    3. Alopecia Secondary to Anti-Tumor Necrosis Factor-Alpha Therapy Anais Brasileiros de Dermatologia · 2015
    4. Alopecia Induced by Tumor Necrosis Factor-Alpha Antagonists: Description of 52 Cases and Disproportionality Analysis in a Nationwide Pharmacovigilance Database Rheumatology · 2014
    5. Psoriatic Scarring Alopecia: A Case Report Anais Brasileiros De Dermatologia · 2013
    6. Tumor Necrosis Factor-Alpha Inhibitor Associated Psoriasiform Alopecia Informa Healthcare eBooks · 2012
    7. Dissecting the Bulge in Hair Regeneration Journal of Clinical Investigation · 2012
    8. Anti-TNF-Alpha Induced Psoriasiform Eruptions with Severe Scalp Involvement and Alopecia: Report of Five Cases and Review of the Literature Dermatology · 2012
    9. Psoriatic Alopecia/Alopecia Areata–Like Reactions Secondary to Anti–Tumor Necrosis Factor-α Therapy: A Novel Cause of Noncicatricial Alopecia The American Journal of Dermatopathology · 2011
    10. Hair Follicle Biology, the Sebaceous Gland, and Scarring Alopecias Archives of dermatology · 1999