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GlossaryTCF4 (Transcription Factor 4)

regulates gene expression crucial for nervous system development

TCF4, or Transcription Factor 4, is a protein that plays a crucial role in regulating the expression of genes involved in various biological processes, including cell growth, differentiation, and development. It is particularly important in the development of the nervous system and has been implicated in several neurological disorders.

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research Stem Cell Heterogeneity and Plasticity in Epithelia

129 citations, May 2015 in “Cell Stem Cell”

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

research Phenotypic Plasticity: Driver of Cancer Initiation, Progression, and Therapy Resistance

403 citations, December 2018 in “Cell stem cell”

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

research Integration of Ethylene and Auxin Signaling and the Developmental Consequences of Their Crosstalk

4 citations, October 2014 in “Springer eBooks”

Ethylene and auxin hormones interact in complex ways that are essential for plant growth and development.

research HDAC6-Dependent Deacetylation of NGF Dictates Its Ubiquitination and Maintains Primordial Follicle Dormancy

January 2024 in “Theranostics”

HDAC6 helps keep ovarian follicles dormant, extending female fertility.

research Incidence of Cicatricial Alopecia Among New Alopecia Patients Undergoing Platelet-Rich Plasma

April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology”

6.1% of patients seeking PRP for hair loss had undiagnosed cicatricial alopecia, which PRP cannot treat.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 768 upvotes 3 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Why is nobody studying the difference between donor and balding hair?

in Chat 89 upvotes 8 months ago

The conversation discusses why the difference between donor and balding hair isn't studied more to find a cure for hair loss. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Fats on your Head to Stop Hair Loss?

in Research/Science 140 upvotes 11 months ago

The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

community HLT Megathread on HMI-115 (key takeaways in comments)

in Research/Science 38 upvotes 2 years ago

HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

community What happened to the ‘funding’ for broccoli research in treating hair loss?

in Chat 41 upvotes 3 years ago

Hair loss discussion includes broccoli sprouts treatment, Fluridil 7%, and sulforaphane, with mixed results. Finasteride, minoxidil, and RU58841 are preferred by some users.

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