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GlossaryImmunoglobulin Transcription Factor 2

protein regulating immune gene expression, especially antibody production

Immunoglobulin Transcription Factor 2 (ITF-2) is a protein that plays a crucial role in regulating the expression of genes involved in the immune system, particularly those related to the production of antibodies. It functions by binding to specific DNA sequences, thereby influencing the transcription of immunoglobulin genes, which are essential for the body's ability to recognize and combat pathogens.

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research Tcf3 Promotes Cell Migration and Wound Repair Through Regulation of Lipocalin 2

55 citations , June 2014 in “Nature Communications”

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

All Roads Lead to the Nucleus: Integration of Signaling, Transcription Factor-Mediated, and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration

research All Roads Lead to the Nucleus: Integration of Signaling, Transcription Factor-Mediated, and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration

January 2018 in “Stem cell biology and regenerative medicine”

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

research Specific Receptor Detection by a Functional Keratinocyte Growth Factor-Immunoglobulin Chimera

66 citations , April 1995 in “The journal of cell biology/The Journal of cell biology”

A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.

research SnapshotDx Quiz: January 2021

December 2020 in “The journal of investigative dermatology/Journal of investigative dermatology”

Papulopustular rosacea is an inflammatory skin condition treatable with lifestyle changes and medications.

research Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development

277 citations , February 2013 in “Science Signaling”

Mitochondrial reactive oxygen species are essential for skin and hair development.

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