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GlossaryImmunoglobulin A

antibody protecting mucous membranes from pathogens

Immunoglobulin A (IgA) is a type of antibody that plays a crucial role in the immune function of mucous membranes. It is found in high concentrations in areas such as the respiratory and gastrointestinal tracts, as well as in saliva, tears, and breast milk, where it helps to neutralize pathogens and prevent infections.

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research Linear Immunoglobulin A/Immunoglobulin G Bullous Dermatosis Associated with Vogt-Koyanagi-Harada Disease

11 citations, May 2011 in “The Journal of Dermatology”

A man had two rare autoimmune diseases that might be connected.

research A Rare Case of Constrictive Pericarditis with Co-Existing Positive COVID-19: Probable Autoimmune or Immunoglobulin Related Disease

April 2021 in “Rheumatology”

An 80-year-old man with COVID-19 also had constrictive pericarditis, possibly due to an autoimmune or immunoglobulin related disease, and improved after surgery.

research Kawasaki Disease: An Update

17 citations, January 2001 in “Clinical and Experimental Dermatology”

Early treatment with immunoglobulin and aspirin reduces heart complications in children with Kawasaki disease.

research Involvement of Mast Cells and CB1 in the Pathogenesis of IgA Vasculitis

April 2023 in “Journal of Investigative Dermatology”

Mast cells and the CB1 receptor may be key in causing IgA vasculitis.

research C002 Vasculitis: A Differential Diagnostic Approach

September 1997 in “Journal of The European Academy of Dermatology and Venereology”

The document concludes that corticosteroids effectively treat vasculitis allergica in over 90% of cases, with long-term kidney issues being the main adverse outcome.

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