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      a topical anti-androgen with less systemic involvement

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      powerful topical and oral anti-androgen used mostly by women

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      a novel topical treatment that inhibits DHT on androgen receptors

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      a potent but unapproved and potentially problematic topical anti-androgen

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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 8 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Being Safe on Oral Minoxidil: tl;dr on the literature.

      in Research/Science  50 upvotes 3 months ago
      Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

      community Topical fin 0.025%, min 5% - 2,5 months progress

      in Finasteride/Dutasteride  9 upvotes 2 weeks ago
      The user started using topical finasteride 0.025% and minoxidil 5% twice daily, seeing initial improvement but later experiencing shedding and scalp pain. They are considering increasing the finasteride dose to 0.05% while using keto shampoo and dermarolling, and are debating the effectiveness of low versus standard doses of finasteride.