September 2022 in “Journal of The American Academy of Dermatology”
This study explored patient attitudes, perceptions, and barriers to using topical minoxidil for hair loss, with most respondents being female and many African American.
This study found that topical formononetin treatment promoted hair regrowth in mice by normalizing hair follicle size and inhibiting apoptosis-related pathways.
7 citations
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July 2020 in “Pigment cell & melanoma research”
In this study, RT1640 was found to promote hair pigment system regeneration and expand melanocyte stem cell pools in a mouse model, suggesting potential applications for aging-related hair disorders.
13 citations
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June 2020 in “Journal of Dermatological Treatment”
This review discusses the pharmacology and safety of topical finasteride for treating androgenetic alopecia and female pattern hair loss, noting positive results but reporting no new clinical findings.
A 42-year-old male experienced hair regrowth using a topicaltreatment of finasteride, ketoconazole, and minoxidil, noticing increased hair density and reduced hair loss over a year. He plans to switch to oral finasteride and continue using topical minoxidil, with a dermatologist's guidance.
Oral biotin combined with topical minoxidil may increase hair growth rate, though the study was limited to healthy subjects and did not measure hair density. Some users report personal benefits from biotin, such as faster nail growth and healthier hair, but concerns about acne and study quality were also mentioned.
A 42-year-old is experiencing hair regrowth after 80 days using oral finasteride and minoxidil, plus topical minoxidil. They are considering additional treatments like dermastamping and possibly switching to dutasteride for further improvement.
Scientists discovered a sugar gel, 2dDR-SA, that increased hair growth in mice. Users discussed its potential, comparing it to other treatments like Minoxidil and finasteride.
Topicaltreatments like minoxidil and finasteride are preferred for hair loss due to ease of use and natural appearance. Hair systems are considered high-maintenance and less genuine.
Is Osteopontin more effective in topicaltreatments or oral supplements for hair loss?Neither route has been tested: there is no published human trial of topical or oral osteopontin for hair loss. The evidence is preclinical, and it points both ways — injected osteopontin promoted hair growth in mice, while an osteopontin-derived peptide suppressed growth in human scalp tissue and its authors proposed it for unwanted hair.