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      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

      learn Minoxidil

      An essential vasodilator with some anti-androgenic effects, has excellent safety record

      learn Fluridil

      a topical anti-androgen with less systemic involvement

      learn RU58841

      a potent but unapproved and potentially problematic topical anti-androgen

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      community New warning by FDA on topical finasteride

      in Research/Science  194 upvotes 5 months ago
      The FDA warned that topical finasteride can cause serious side effects like sexual dysfunction and brain fog, similar to oral finasteride. Compounded topical formulations pose additional risks due to lack of regulation.

      community MY 6 MONTH TRANSFORMATION PROGRESS

      in Progress Pictures  210 upvotes 1 year ago
      A 23-year-old male shared his 6-month hair transformation using Dutasteride, oral Minoxidil, ketoconazole shampoo, vitamin D, gym, cardio, and dermastamping. He reported significant hair maintenance and no side effects.

      community PP405 2a study was a safety study. Some rational explaining.

      in Research/Science  22 upvotes 1 month ago
      The conversation discusses the safety study of PP405, emphasizing that early trials focus on safety rather than efficacy, and that any efficacy data from such a short study should be viewed skeptically. It also highlights that the information released is primarily for securing funding, and that meaningful efficacy results are expected in later phases.