August 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” This article reviews current treatments for alopecia areata, discussing the potential role of JAK inhibitors and noting the need for further clinical trials, but it reports no new results.
June 2023 in “Zenodo (CERN European Organization for Nuclear Research)” January 2004 in “Drug Development and Industrial Pharmacy” This study explored the solubility and crystal structure of GI197111X, a 5-alpha reductase inhibitor for androgenetic alopecia, finding its solubility in Capmul MCM suitable for a soft gel dosage form.
June 2023 in “Zenodo (CERN European Organization for Nuclear Research)”
8 citations
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September 2017 in “Journal of Investigative Dermatology” This study found that inhibiting the interaction between CXXC5 and Dishevelled could stimulate hair regrowth in mouse models by enhancing WNT/β-catenin signaling, suggesting a potential therapeutic strategy for hair loss involving compounds that block this interaction, such as interfering short peptides.
152 citations
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April 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” This study presents evidence that keratitis–ichthyosis–deafness syndrome is caused by a mutation in the connexin 26 gene, expanding the gene's known involvement in various disorders.
5 citations
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August 2013 in “Epilepsy & Behavior” 11 citations
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April 2022 in “Journal of Dermatological Treatment” This review found evidence supporting zinc use in treating infectious and inflammatory skin conditions, as well as hair loss, with supplementation recommended for zinc-deficient patients.
3 citations
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September 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that enhanced wound healing in oral mucosa involves a SOX2-regulated transcriptional network which includes increased expression of keratin K75, and interaction of K75 with the LINC complex may play a crucial role in promoting rapid wound repair.
May 2026 in “Research Square” This research reports that the polyG fragment within the Hoxc13 protein alters its gene regulatory functions, which could have influenced mammalian hair evolution by affecting pathways related to hair follicle development.
18 citations
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July 2006 in “British Journal of Dermatology” This study reported no Cx30 expression in normal interfollicular human epidermis and minimal expression in some skin structures, with faint detection in porokeratosis of Mibelli patient skin.
February 2022 in “Journal of Innovative Science and Engineering (JISE)” This review discusses synthetic piezoelectric polymers within the smart polymer family, detailing their applications in various medical fields, but reports no new experimental results.
13 citations
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January 2017 in “Annals of dermatology/Annals of Dermatology” In this study, simvastatin/ezetimibe treatment led to partial hair regrowth in about 29% of patients with recalcitrant alopecia areata, suggesting it may be a viable alternative therapy for this condition.
10 citations
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August 2010 in “Hereditas (Beijing)” This review summarizes the role of Hoxc13 in regulating hair follicle development and growth, noting its influence on keratin and keratin-associated proteins, and reports no new experimental findings.
34 citations
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April 1982 in “BMJ” June 2026 in “Journal of Ethnopharmacology” September 2023 in “Zenodo (CERN European Organization for Nuclear Research)” 11 citations
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March 2023 in “Frontiers in Nutrition” This study found that a modest increase in dietary zinc over six months resulted in a detectable increase in sulfur and zinc counts in individual hairs, suggesting a non-invasive method to monitor zinc intake effects.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study shows that IKZF1 and the protein IKAROS may play a role in the development of alopecia areata, based on findings from both mouse models and human scalp tissues.
January 2023 in “Zenodo (CERN European Organization for Nuclear Research)” This abstract discusses the FitSpresso weight loss supplement's potential benefits and mechanisms but provides no clinical research findings; it reports on its ingredients and consumer ratings instead.
Deuruxolitinib effectively promotes hair regrowth in alopecia areata.
January 2000 in “Medical Entomology and Zoology”
May 2023 in “Advancements in Homeopathic Research” This study investigated the effectiveness of a botanical formulation, Zauberӧl®, on testosterone-induced alopecia in Wistar rats, focusing on ingredients such as Arnica montana and Hibiscus Rosa sinensis. Results are not reported in the abstract.
1 citations
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December 2007 in “Journal of Microbiology and Biotechnology” This study found that Minoxidil included in triamino alpha-cyclodextrin significantly promoted hair growth in mice, potentially due to its enhanced substantivity on skin.
December 2022 in “Journal of Pakistan Association of Dermatologists” This review highlights zinc's role in health and disease, noting its involvement in immune function and its therapeutic potential for conditions like alopecia areata and psoriasis, but it reports no new clinical results.
9 citations
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November 2021 in “Frontiers in Cell and Developmental Biology” This study found that PBX1 overexpression reduces hair follicle-derived mesenchymal stem cell senescence and apoptosis by alleviating ROS-mediated DNA damage, rather than enhancing DNA repair.
6 citations
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November 2022 in “Journal of Tissue Engineering and Regenerative Medicine” This study found that while zebularine did not significantly accelerate wound healing, it improved the quality of restored skin in mice, suggesting potential for further research into epigenetic inhibitors.
August 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reports that a patient with rare linear lichen planopilaris experienced complete hair regrowth after 12 weeks of treatment with the antibody ixekizumab, suggesting it as a potential targeted therapy.
1 citations
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September 2023 in “Genes” This study found no significant difference in CUX1 core promoter methylation levels between different lambskin patterns in Hu sheep, suggesting other mechanisms influence CUX1 expression related to hair follicle development.
16 citations
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March 2021 in “EvoDevo” This study found that zebrafish and sticklebacks, despite differences in their tooth regeneration structures, share a similar genetic program during tooth regeneration, suggesting a conserved "successional dental epithelium" in vertebrates.