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New drugs for Alzheimer's and rheumatoid arthritis advanced, a Zika vaccine is in development, and there were business deals in anesthesia and oncology.

In a post-hoc analysis of six trials, this study observed that both adult and pediatric patients with moderate-to-severe palmoplantar psoriasis treated with ixekizumab experienced rapid and complete clearance of lesions, sustained for up to 5 years in adults and 2 years in children.

This systematic review identified topical and oral minoxidil as the most effective treatments for monilethrix, but noted the varying efficacy of oral retinoids and other treatments.

This case report describes a 61-year-old Italian man with a rare, localized variant of junctional epidermolysis bullosa linked to the R795X mutation in the COL17A1 gene, highlighting the importance of precise diagnosis for effective management of rare genetic disorders.

This study reports the first case of eyelash elongation and thickening in a patient with hypereosinophilic syndrome taking the Janus kinase inhibitor ruxolitinib.

This archived website overview discusses Bioline International's role in reducing the knowledge gap by hosting peer-reviewed journals from developing countries but presents no new research findings.

This paper creatively examines whether the name "Janus" in Janus kinase inhibitors foreshadows their dual role in the treatment of dermatological conditions, drawing parallels to the Roman god Janus's dual nature and influence over beginnings and transitions.

In this study, dexpanthenol exhibited antiepileptic and antidepressant-like effects in mice without impacting their motor coordination.

Adding zinc to pyrithione zinc improves its effectiveness against scalp conditions like dandruff.

This case report on a 13-year-old boy with monilethrix observed slight improvement after a two-month trial of oral N-acetyl cysteine, but overall hair density did not improve further.

This study observed distinct changes in the ultrastructure of Hexi cashmere goat hair follicles throughout the year, highlighting stages with specific cellular and structural characteristics.

In this study, inducing zinc deficiency in recently weaned female Tan rabbits led to reduced food consumption, weight loss, and reproductive issues, including inactive uterine and ovarian changes.

This study involving 81 yaks found significant correlations between melatonin, dihydrotestosterone, and immunoglobulin levels in blood serum and mineral content in hair, suggesting these factors may jointly influence yak hair growth and immune status, providing a potential non-invasive indicator of overall health.

This study proposes that seasonal alopecia and reproductive changes in six female fossas at the San Diego Zoo may be linked to hormonal changes associated with reproductive activity.

This study highlights the potential role of the CYP21A2 and CYP19A1 genes in severe acne vulgaris among Han Chinese, especially males.

This case report of an infant with IPEX syndrome highlights the importance of early recognition and treatment, as the patient experienced severe symptoms and succumbed before stem cell transplantation.

In this chemical investigation, cyclospongiaquinone 1 from the sponge Verongula cf. rigida showed strong steroid 5α-reductase inhibitory activity, comparable to that of finasteride.

This study found that the Lim-homeodomain transcription factor Lhx2 regulates Sonic Hedgehog signaling during early retinal neurogenesis in mice by controlling the expression of pathway genes in retinal progenitor cells.

This review discusses how sex-limited chromosomes can affect non-reproductive traits in various sex determination systems and reports no new empirical results.

Ozenoxacin 1% cream is an effective and safe treatment for impetigo in children and adults.

This article describes a case of hypertrichosis potentially induced by using efalizumab but provides no new clinical study results.

In this study, ozenoxacin was found to inhibit sebum production in insulin- and 5α-DHT-differentiated hamster sebocytes in a dose-dependent manner, suggesting potential benefits in acne management by combining antimicrobial activity against C. acnes with reduced sebum production.

This study found that the GPRC6A-Duox1 signaling pathway influences hair cycle progression and testosterone-mediated hair loss in mice, suggesting that disruption of this pathway leads to resistance against testosterone-induced hair loss and longer anagen phase duration.

In this study, researchers identified two de novo germline missense mutations in the hair keratins hHb1 and hHb6 in patients with monilethrix whose parents were not clinically affected.

Certain substances can protect against ear damage from some antibiotics in zebrafish.

This study establishes a robust analytical method using mass spectrometry to comprehensively identify 170 chemical compounds in Xiaoban Kangfu capsules for enhanced quality control.

In this study, overexpression of YAP1 was found to promote adipogenic differentiation of goat adipose-derived mesenchymal stem cells by up-regulating LATS2 expression and activating the Hippo pathway's negative feedback loop.

The researchers reported that yak hair fibers undergo macromolecular conformational changes and partial slippage of macromolecules during stretching, confirming this as the main stretching mechanism when the stretching ratio is large.

This study reported that high-dose mizoribin therapy may be effective and safe for managing steroid-dependent pediatric systemic lupus erythematosus but requires monitoring of serum uric acid levels due to potential side effects.

This review explores the advantages and limitations of using zebrafish models to study various skin diseases, but reports no new experimental results.