September 2018 in “Reactions Weekly” Two women had skin reactions from a hair loss treatment and got better after stopping use.
2 citations
,
March 2016 in “Düşünen Adam” This case report describes alopecia associated with escitalopram use, which improved upon switching to duloxetine, and examines existing literature on antidepressant-related hair loss.
January 2012 in “Medical Journal of Babylon”
1461 citations
,
March 2004 in “Annals of oncology” This study found that in first-line treatment of metastatic breast cancer, pegylated liposomal doxorubicin (PLD) provided similar progression-free survival to doxorubicin with significantly less cardiotoxicity.
This trial will compare the effectiveness of spironolactone to doxycycline for treating acne in adult females, potentially offering an alternative to antibiotics and isotretinoin.
53 citations
,
June 1993 in “Proceedings of the National Academy of Sciences of the United States of America” This study identified LY191704 as a specific noncompetitive inhibitor of human 5 alpha-reductase type 1, which may be useful in treating endocrine disorders related to DHT overproduction.
14 citations
,
November 2018 in “Journal of drug delivery and therapeutics” This article reviewed the preparation, application, and characterization of ethosomes as drug delivery transporters and reported that in a double-blind randomized clinical study, ethosomal acyclovir significantly improved all evaluated parameters in skin delivery, highlighting potential for novel therapies.
September 2024 in “Journal of the American Academy of Dermatology” In this prospective, placebo-controlled study, the researchers observed a significant reduction in hair shedding in women after applying the combined topical treatment DA-OTC-002, containing synephrine and TAAR agonists, compared to placebo, showing a 62.5% average reduction with no reported adverse events.
August 2021 in “Pediomaternal Nursing Journal” This study concluded that clomiphene citrate is generally preferred over metformin for inducing ovulation in obese women with PCOS, despite low-quality evidence indicating metformin may be superior to placebo for live births.
14 citations
,
July 2007 in “Therapy” This review discusses ethosomes as potential carriers for delivering drugs into deeper skin layers and provides no new clinical results, suggesting a need for further studies on their efficiency in dermal therapies.
182 citations
,
January 2000 in “Drug Development Research” This study found that ethosomal carriers enhanced dermal and transdermal drug delivery more effectively than classic liposomes, improving delivery to deep skin layers and showing potential for treating conditions like herpes labialis and diabetes.
June 2015 in “Reactions weekly” December 2012 in “Reactions weekly” May 2024 in “Reactions weekly” February 2006 in “Inpharma Weekly”
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This paper discusses ethosomal drug delivery systems, highlighting their improved ability to enhance skin penetration and increase therapeutic effectiveness in treatments like acyclovir for herpes labialis and minoxidil for androgenic alopecia compared to standard formulations.
October 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This source describes Protetox as a natural dietary supplement that aids in weight loss by detoxifying the body, utilizing a blend of plant-based ingredients and antioxidants, and claims users have reported significant weight loss without changing their diet or exercise routines.
This study found that a combination of spironolactone and oral contraceptive pills may improve hirsutism and hormonal profiles in women, although some experienced side effects such as persistent nausea.
7 citations
,
March 2013 in “Tetrahedron Letters” This study reports a new one-pot method for synthesizing chromeno-pyrimidine-N-oxides with high yield from 4-chloro-3-formylcoumarin and aromatic carboximide oximes, confirmed by X-ray analysis.
January 2025 in “Brazilian Journal of Veterinary Medicine/Revista Brasileira de Medicina Veterinária” This source describes the first successful use of a deslorelin acetate implant to treat alopecia X in a neutered female dog, achieving profuse hair regrowth in 9 months, suggesting an uncomplicated and cost-effective alternative after melatonin failure.
This study found that ingesting seeds from the Lecythis ollaria tree may cause hair loss and other toxic effects in animals.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that the Keyora Lycopene 23 in 1 formulation may improve various aspects of male endocrine and reproductive health by targeting oxidative stress, nitric oxide deficiency, and hormonal imbalance.
August 2026 in “International Journal of Dermatology” This article discusses the availability of data from TriNetX for research purposes and reports no new findings.
November 2010 in “Clin-Alert” Monitoring for adverse effects in clinical treatments is crucial.
109 citations
,
March 2011 in “Journal of controlled release” This study found that econazole nitrate delivered via MPEG-dihexPLA micelles significantly increased skin deposition compared to Pevaryl® cream, potentially enhancing drug bioavailability and clinical efficacy.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study reports that ethosomal formulations, such as ethosomal acyclovir and minoxidil, improved therapeutic effectiveness by enhancing skin permeation, leading to faster healing of herpes labialis lesions and increased skin absorption compared to standard formulations.
July 2024 in “Journal of Investigative Dermatology” Most women continued using oral minoxidil for hair loss despite mild to moderate side effects.
29 citations
,
February 2007 in “Hormone and metabolic research” This study found that antisense oligonucleotides can significantly reduce androgen receptor expression in cultured human sebocytes and may offer new therapeutic possibilities for androgen-associated skin diseases.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, the researchers introduced the Keyora Lycopene 23 in 1 formulation, demonstrating its potential to improve male endocrine and reproductive health by addressing oxidative stress, nitric oxide deficiency, androgen imbalance, and mitochondrial dysfunction through a comprehensive multi-nutrient approach.