21 citations
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January 2014 in “International Journal of Trichology” This study observed that while dermoscopic features in alopecia areata for dark-skinned individuals align with existing literature, yellow dots appear more frequently and could help in grading disease severity.
1 citations
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June 2023 in “Cosmoderma” This study found that in patients with alopecia areata, trichoscopy was a valuable tool for monitoring disease activity, severity, and therapeutic response, showing changes in trichoscopic markers that preceded improvements observed in the hair pull test.
3 citations
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January 2017 in “Yonsei Medical Journal” This study found that inhibiting 11β-HSD1 can partially reverse the negative impact of glucocorticoids on dermal papilla cells in human scalps, suggesting potential for treating stress-related hair loss.
This review discusses various non-invasive methods for diagnosing alopecia areata, highlighting that trichoscopy signs like short vellus hairs and yellow dots are sensitive indicators of the condition, while advanced imaging techniques provide valuable information on hair follicle status and scalp inflammation.
October 2021 in “International journal of research in dermatology” This study found no significant associations between dermoscopic findings and the severity or stage of alopecia areata in children, though there was a notable correlation with nail findings.
1 citations
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December 2018 in “Journal of Pakistan Association of Dermatology” This study reported that different types of alopecia have distinctive dermoscopic patterns, which aids in their diagnosis.
January 2025 in “Journal of Rawalpindi Medical College” In this study, among 800 Pakistani patients with Alopecia Areata, the most common location for hair loss was the scalp (89.9%), with significant associations between age and various dermoscopic features like black dots and exclamation mark hairs.
June 2019 in “Journal of evolution of medical and dental sciences” This study found that yellow dots seen under dermatoscopy are a sensitive and specific indicator of treatment response in alopecia areata, showing significant reduction as early as four weeks.
30 citations
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April 2021 in “The Journal of Sexual Medicine” This guideline provides recommendations for prescribing systemic testosterone to women with hypoactive sexual desire disorder, emphasizing safe dosing, monitoring, and the need for informed consent despite regulatory challenges.
14 citations
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April 2017 in “Dermatology practical & conceptual” This study reports that yellow dots in a higher number per field of vision were the most consistent dermoscopic finding in severe cases of alopecia areata.
33 citations
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December 2005 in “British Journal of Clinical Pharmacology” This study found that the Transdermal Delivery System efficiently delivers testosterone systemically and showed bioequivalent hormone concentrations to a known topical gel in healthy males.
6 citations
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January 2015 in “Biochemical Society Transactions” This review discusses the role of Ysc84/SH3yl1 proteins in linking actin regulation to membrane morphology changes but reports no new experimental results.
August 2015 in “International Journal of Genetics and Molecular Biology” This study found that specific Y-chromosome alleles may influence susceptibility to prostate cancer in Iraqi males, suggesting their potential use in screening for the disease.
15 citations
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October 2010 in “Archives of Toxicology” This study found that the yeast androgen screen (YAS) could detect the activity of methyltestosterone in urine for a longer period than classical GC/MS, potentially identifying long-lasting metabolites.
September 2022 in “Annals of medicine and surgery” This case report discusses the diagnostic challenges and management options for three siblings with 46, XY DSD due to type 2 5-α reductase deficiency, highlighting the genetic basis and impact on their quality of life.
January 2024 in “Wiadomości Lekarskie” This pilot clinical study introduces DEC cells as a novel therapy for Duchenne muscular dystrophy, confirming safety and efficacy in seven patients up to 24 months post-treatment.
3 citations
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February 2019 in “Disease Markers” This study reports that a lower 2D:4D finger length ratio is significantly associated with higher disease activity and reduced spinal mobility in females with ankylosing spondylitis, but not in males.
2 citations
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July 2015 in “Case Reports in Dermatology” In this case study, DDS treatment for LABD was complicated by hemolytic anemia and alopecia, suggesting the need for careful monitoring of these potential side effects.
1 citations
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April 2019 in “Journal of Investigative Dermatology” This study examined the safety and efficacy of dupilumab in adolescents with moderate-to-severe atopic dermatitis, finding that it was well tolerated and significantly improved symptoms over 52 weeks, with its safety profile similar to that in adults.
July 2024 in “Journal of Investigative Dermatology” In these two clinical trials, DS-2325a, a KLK5 inhibitor, was found to be generally safe and well tolerated in healthy volunteers, with mild and non-serious adverse events, suggesting its potential for further development as a treatment for Netherton Syndrome.
54 citations
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April 2010 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” This review discusses 46,XY disorders of sex development caused by defects in androgen production and highlights the need for long-term care from experienced multidisciplinary teams, but it reports no new clinical findings.
3 citations
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April 2015 in “AFRICAN JOURNAL OF BIOTECHNOLOGY” This study found that certain Y-chromosome alleles may influence susceptibility to prostate cancer among Iraqi males, suggesting potential genetic screening markers for the disease.
This review found an increased prevalence of common skin disorders, such as infectious and inflammatory conditions, in patients with Down syndrome and highlighted the need for improved screening and management guidelines.
2 citations
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September 2023 in “Journal of the Egyptian Womenʼs Dermatologic Society” This study concluded that exclamation mark hairs are the most reliable marker of disease activity in alopecia areata, with broken hairs, triangular hairs, and black dots also increasing the probability of active disease.
1 citations
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January 2019 in “Journal of the Egyptian Women's Dermatologic Society (Print)” This study observed that while both minoxidil and botanically-derived 5-alpha reductase inhibitors significantly increased hair count and diameter in women with female pattern hair loss, minoxidil was more effective, especially for greater hair diameter increases, but had more troublesome side effects.
May 2026 in “Journal of the Egyptian Womenʼs Dermatologic Society” In this prospective study, 15 patients with patchy alopecia areata treated with intralesional methotrexate every two weeks showed a significant improvement in hair regrowth and reduction in lesion severity, with changes linked to decreased tissue levels of TNF-α.
October 2025 in “Cell Transplantation” This review discusses recent advancements in hair loss treatments, including stem cell and hair follicle cell therapies, growth factors, extracellular vesicles, gene therapy, and tissue engineering, highlighting their potential in improving hair regeneration and follicle health.
April 2025 in “Clinical Dermatology Review” In this study, researchers reported that dermatoscopy effectively differentiates between various types of alopecia and scalp disorders, offering a fast, minimally invasive diagnostic method that improves the standard of care and reduces the necessity for scalp biopsies.
January 2025 in “Journal of the Egyptian Womenʼs Dermatologic Society” In this study, both fractional carbon dioxide laser therapy and cryotherapy were found to be effective and safe for treating patchy alopecia areata, showing similar efficacy in improving hair growth compared to untreated control patches.
28 citations
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August 2001 in “Journal of cutaneous medicine and surgery” This review discusses the increased incidence of dermatological conditions in individuals with Down's syndrome and explores potential links to immunological deficiencies, but reports no new clinical findings.