37 citations
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January 1986 in “Carcinogenesis” This study found that TPA treatment transiently induces high levels of ODC in mouse epidermal cells, particularly around hair follicles, with localization reduced by retinoic acid or cycloheximide pretreatment.
22 citations
,
April 2012 in “The American journal of pathology” This study found that the loss of Msx2 in knockout mice led to phenotypes similar to Peters anomaly and microphthalmia, suggesting that MSX2 plays a critical role in anterior segment development of the eye.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This phase 2a trial evaluated Samcyprone for common wart treatment and found that while a sensitization reaction is necessary for therapeutic response, its level does not predict wart clearance.
1 citations
,
December 2022 in “Life” This review systematically analyzed evidence on treatment options for erosive pustular dermatosis, finding that while potent topical steroids like clobetasol propionate can be effective, recurrence is common, and more robust studies are necessary for stronger recommendations.
3 citations
,
May 2018 in “European Journal of Dermatology” Photodynamic therapy may not work for erythroplasia of Queyrat and could lead to invasive squamous cell carcinoma.
February 2025 in “Journal of the European Academy of Dermatology and Venereology” This study found that epidermal growth factor receptor inhibitors can induce erosive pustular dermatosis of the scalp, typically appearing sooner and affecting the scalp more extensively compared to other triggers.
13 citations
,
February 2007 in “British Journal of Dermatology” EF and PXE not closely related.
17 citations
,
August 2012 in “Journal of Medical Genetics” This article reviews the genetic mutations associated with hypohidrotic ectodermal dysplasia and reports no new clinical results; the authors highlight the roles of EDA gene isoforms and related receptors.
5 citations
,
September 2014 in “Journal of Pharmaceutical Sciences” 8 citations
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June 2021 in “Frontiers in Medicine” This study reported that the combination of a 308-nm excimer lamp and 10% liquor carbonis detergens significantly improved scalp psoriasis symptoms compared to the excimer lamp alone, with more patients achieving 75% reduction in their Psoriasis Scalp Severity Index.
1 citations
,
July 2024 in “Journal of Investigative Dermatology” Plaquenil can cause a severe skin reaction called AGEP, requiring prompt diagnosis and treatment.
13 citations
,
January 2021 in “Scientific Reports” This study found that Pannexin 3 plays a crucial role in skin development by regulating the transcription factor Epiprofin, affecting keratinocyte differentiation and hair follicle regeneration in mice.
July 2022 in “Dermatology Reports” This report details a case of a 58-year-old male diagnosed with erosive pustular dermatosis of the scalp, which improved following 3-5 weeks of treatment with topical clobetasol proprionate.
This study found that an extract treatment showed similar efficacy and tolerability to calcipotriol/betamethasone ointment in reducing psoriasis severity and symptoms over 28 days in patients with mild-to-moderate plaque psoriasis.
September 2016 in “Journal of Dermatological Science” This study reports a case of GGCX syndrome in a 55-year-old Japanese male, characterized by PXE-like symptoms and coagulation deficiency, with an unreported phenotype of possible spinocerebellar degeneration.
5 citations
,
September 2020 in “Journal of Cosmetic Dermatology” This study reported that weekly intramuscular dexpanthenol may improve quality of life and satisfaction with hair appearance in women with female pattern hair loss, with no side effects observed.
April 2017 in “Journal of Investigative Dermatology” This study found that the PON1 192 R allele was associated with an increased risk of psoriasis and altered lipid profiles in patients from Western Mexico.
10 citations
,
June 2011 in “Archives of Dermatology” Finasteride caused blisters on hands and feet.
1 citations
,
July 2015 in “British Journal of Dermatology” Imiquimod improved skin pigmentation in most patients with xeroderma pigmentosum and may prevent further skin cancer, but some treatments can have side effects.
3 citations
,
April 2024 in “Molecular Human Reproduction” This study found that paxillin knockdown in human granulosa-derived cells and mouse models decreased androgen receptor protein levels and altered gene expression, suggesting paxillin's role in protecting against androgen excess effects, as observed in a polycystic ovary syndrome mouse model.
80 citations
,
April 2017 in “Frontiers in Pharmacology” This review examines experimental and clinical evidence on PDRN, a drug derived from salmon DNA that acts via the adenosine A2A receptor and shows promise for tissue repair and treatment of diabetic foot ulcers in regenerative medicine.
3 citations
,
July 2018 in “Elsevier eBooks” This case report describes an elderly man with erosive pustular dermatosis of the scalp, who improved with potent topical corticosteroids followed by maintenance with topical tacrolimus.
9 citations
,
January 2020 This case series observed that macular changes from popper use can resolve completely after cessation, even in individuals with chronic use.
16 citations
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October 2013 in “Anais Brasileiros de Dermatologia” In this case report, an elderly woman with erosive pustular dermatosis of the scalp showed complete closure of eroded areas after treatment with prednisone and topical tacrolimus, resulting in stable scarring alopecia.
253 citations
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April 2009 in “Journal of Biological Chemistry” This study found that p2y5 functions as a novel LPA receptor involved in the G13-Rho signaling pathway, with implications for human hair growth, and proposes renaming it to LPA6.
80 citations
,
April 2011 in “Plant physiology” This study suggests that the GPX-PDE1 and GPX-PDE2 genes in white lupin enhance root hair development and contribute to Pi limitation acclimation by facilitating glycerophosphodiester degradation.
15 citations
,
June 2019 in “Biochemical Journal” This study identified a heterozygous de novo mutation in the ODC1 gene causing a new disorder characterized by overgrowth and developmental delay, and suggests that DFMO treatment may help manage elevated ODC activity and putrescine levels.
9 citations
,
August 2002 in “Current Opinion in Pediatrics” This article discusses the roles of pediatrics and dermatology departments at Yale University School of Medicine, but reports no specific clinical results.
8 citations
,
January 2013 in “Medicinal chemistry” This study reported that among 10 tested 2-(4-chlorophenyl)-5-aryl-1,3,4-oxadiazole compounds, compound 4c showed the highest activity against cancer cell lines, with a 95.37% average growth rate.
87 citations
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March 2017 in “Journal of Clinical Investigation” In this study, researchers identified PSENEN mutations that can lead to a form of Dowling-Degos disease, characterized by follicular hyperkeratosis and an increased susceptibility to acne inversa, especially in the presence of certain trigger factors.